Evidence map›Paper›PMID 39606803›Full record

ArticleCancer medicine2024

Improved Effectiveness of Combined Screening for Multiple Cancers: A Government-Organized Population-Based Study in China.

Qian Lu, Di Liang, Jin Shi, Siqi Wu, Xinyu Du, Yutong He

Abstract read
In one paragraph

Article in Cancer medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qian LuCancer Institute in Hebei Province, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.ORCID 0009-0005-5132-0412
Di LiangCancer Institute in Hebei Province, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Jin ShiCancer Institute in Hebei Province, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Siqi WuCancer Institute in Hebei Province, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.ORCID 0000-0002-4460-5904
Xinyu DuCancer Institute in Hebei Province, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Yutong HeCancer Institute in Hebei Province, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe purpose of this study was to analyze the effectiveness of the Cancer Screening Program in Urban China (CanSPUC) in Hebei Province, 2016-2023.

methodsA questionnaire for risk factors of lung, breast, upper gastrointestinal, liver, and colorectal cancers was administered to urban residents aged 40-74 years in five cities to assess their cancer risk. High-risk participants were invited for screening and classified into five groups on the basis of the number of cancer types that were assessed to be high risk. The participation and positive outcome rates were analyzed. The incidence and the mortality of five types of cancer and all-cause mortality of the screened and nonscreened participants were calculated via inverse probability weighting.

resultsA total of 237,975 eligible participants were enrolled in our study and 118,339 participants (49.94%) were assessed to be at high risk for one or more of the five cancer types. The number of screenings performed was 103,824, with a screening participation rate of 40.49%. Among the 57,315 screening participants, 9077 (15.84%) had positive cancer diagnoses and 871 (1.52%) were diagnosed with suspected cancer. Compared with the participants at high risk for a single cancer type, the participation and positive outcome rate increased by 45% and 71.5% in the participants at high risk for multiple cancer types. Compared with the non-screened participants, the screened participants had a 27.0% decrease in mortality due to the five types of cancer and a 45.8% decrease in all-cause mortality.

conclusionA combined screening program for multiple cancers could increase participation and positive outcome rates. It could also decrease the five types of cancer mortality and all-cause mortality. Our findings highlight the effectiveness of combined screening for multiple cancers with limited health care resources, and may provide foundational evidence for the feasibility of conducting combined screening programs.

Indexed as

Early Detection of CancerAdultAgedChinaFemaleHumansIncidenceMaleMass ScreeningMiddle AgedNeoplasmsNeoplasms, Multiple PrimaryRisk FactorsSurveys and Questionnairescancercomplianceeffectivenessrisk assessmentscreening

Identifiers

PMID39606803
PMCPMC11602753

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.