Evidence map›Paper›PMID 39606683›Full record

ArticleAvicenna journal of medical biotechnology

The Effect of Simulated Physiological Oocyte Maturation (SPOM) and L-Carnitine on Bovine Oocyte Developmental Competence.

Ali Malekpour, Abolfazl Shirazi, Sara Borjian Boroujeni, Ali Sarvari, Mohammad Mehdi Naderi, Mostafa Pournourali, Bahareh Behzadi, Mohammad Mehdi Mehrazar

Abstract read
In one paragraph

Article in Avicenna journal of medical biotechnology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Extracellular vesicles: key mediators inFrontiers in veterinary science · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ali MalekpourReproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
Abolfazl ShiraziReproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
Sara Borjian BoroujeniReproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
Ali SarvariReproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
Mohammad Mehdi NaderiReproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
Mostafa PournouraliReproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
Bahareh BehzadiReproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
Mohammad Mehdi MehrazarReproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Simulated Physiological Oocyte Maturation (SPOM) mimics Methods: Ovarian Cumulus Complexes (COCs) were cultured in the presence or absence of forskolin+IBMX during the first 2 Results: The cleavage and blastocyst rates in the Pre-IVM and Pre-IVM/LC groups was higher than control group and other groups (p≤0.05) except for IVC/LC and IVM/LC groups, respectively. The number of blastocyst's Inner Cell Mass (ICM) in pre-IVM and Pre-IVM/LC groups as well as the ratio of ICM/TE were higher than control group (p<0.05). The expression of OCT4, CDX2, and IFNT increased in both the pre-IVM and pre-IVM/LC groups compared to the control group (p<0.05). Conclusion: In conclusion, the application of SPOM-adapted IVM and L-carnitine during IVM of bovine oocyte improves the quantity and quality of the resulting embryos.

Indexed as

3-Isobutyl-l-methylxanthinebcl-2-associated X proteinBlastocystCarnitineCattleMeiosisOocytesPre-IVM

Identifiers

PMID39606683
PMCPMC11589426

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.