Evidence map›Paper›PMID 39606548›Full record

ArticleCureus2024

Nonoperative Management of Boerhaave Syndrome: A Case Study.

Maria Konstantina Tzioti, Alexandra Marinou, Theodoros Sidiropoulos, Anastasia Karachaliou, Nikolaos Danias

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Boerhaave Syndrome-Narrative Review.Diagnostics (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maria Konstantina TziotiSchool of Medicine, National and Kapodistrian University of Athens, Athens, GRC.
Alexandra MarinouSchool of Medicine, National and Kapodistrian University of Athens, Athens, GRC.
Theodoros Sidiropoulos4th Department of Surgery, "Attikon" University Hospital, National and Kapodistrian University of Athens, Athens, GRC.
Anastasia Karachaliou2nd Department of Radiology, "Attikon" University Hospital, National and Kapodistrian University of Athens, Athens, GRC.
Nikolaos Danias4th Department of Surgery, "Attikon" University Hospital, National and Kapodistrian University of Athens, Athens, GRC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spontaneous esophageal rupture, also known as Boerhaave syndrome, represents an unusual yet clinically significant condition characterized by the rupture of the esophageal wall due to a sudden increase in intraluminal pressure, typically induced by vomiting, concomitant with negative intrathoracic pressure dynamics. This condition poses a challenging clinical entity, presenting high mortality rates, especially when treatment is delayed. Surgical intervention is frequently employed as the primary management strategy, while non-surgical approaches, including stent placement and endoluminal vacuum therapy, are less commonly utilized. This study aims to provide insights into the efficacy of non-operative management strategies by examining a clinical case. A 20-year-old male patient presented with fever, epigastric pain, excessive vomiting, and diarrhea over the past four days. A week prior, he had been examined at a private clinic, diagnosed with acute appendicitis, and managed conservatively with oral antibiotics. On the current admission, a contrast-enhanced thoracoabdominal CT scan revealed pneumomediastinum without fluid collection and portal vein thrombosis evidently due to acute appendicitis. Given the patient's favorable clinical status and the absence of collections in the mediastinum, a nonoperative approach was decided upon and was eventually successful. This case study concerns the sensible application of conservative modalities in selected patients with esophageal rupture.

Indexed as

boerhaave syndromeesophageal rupture after vomitingesophageal rupture treatmentnonoperative management of rupturespontaneous esophageal rupture

Identifiers

PMID39606548
PMCPMC11602207

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.