ArticleCureus2024
Nonoperative Management of Boerhaave Syndrome: A Case Study.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Diagnostic Approach and Therapeutic Management of Spontaneous Esophageal Perforation (Boerhaave's Syndrome): A Systematic Review and Individual Patient-Level Pooled Analysis.Journal of clinical medicine · 2026Review
- Boerhaave Syndrome-Narrative Review.Diagnostics (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spontaneous esophageal rupture, also known as Boerhaave syndrome, represents an unusual yet clinically significant condition characterized by the rupture of the esophageal wall due to a sudden increase in intraluminal pressure, typically induced by vomiting, concomitant with negative intrathoracic pressure dynamics. This condition poses a challenging clinical entity, presenting high mortality rates, especially when treatment is delayed. Surgical intervention is frequently employed as the primary management strategy, while non-surgical approaches, including stent placement and endoluminal vacuum therapy, are less commonly utilized. This study aims to provide insights into the efficacy of non-operative management strategies by examining a clinical case. A 20-year-old male patient presented with fever, epigastric pain, excessive vomiting, and diarrhea over the past four days. A week prior, he had been examined at a private clinic, diagnosed with acute appendicitis, and managed conservatively with oral antibiotics. On the current admission, a contrast-enhanced thoracoabdominal CT scan revealed pneumomediastinum without fluid collection and portal vein thrombosis evidently due to acute appendicitis. Given the patient's favorable clinical status and the absence of collections in the mediastinum, a nonoperative approach was decided upon and was eventually successful. This case study concerns the sensible application of conservative modalities in selected patients with esophageal rupture.
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Registered trials
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