ArticleCureus2024
Impact of an Active Nutrition Program on Weight Loss and Metabolic Health in Overweight and Obese Adults: A Randomized Controlled Trial.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of this study was to evaluate the impact of a 60-day low-calorie nutrition-rich diet plan compared to usual care on weight loss, physiological factors, markers of metabolic health, and perceived wellness.
methodsOverweight or obese adults (N = 60) were randomly assigned to either the active nutrition group (n = 30) or the usual care group (n = 30). The active nutrition plan consisted of two meal replacement shakes, an electrolyte replacement drink, a metabolic support supplement, one whole food meal, and three to five servings of whole food snacks (e.g., vegetables and fruits), which totaled approximately 1200-1600 calories daily. Participants were evaluated at baseline and 30- and 60-day follow-ups for mean changes in anthropometric characteristics, biochemical variables, self-reported feelings of health and well-being, and dietary intake.
resultsOf the 60 participants, 49 were women and 11 were men, with a mean age of 38 ± 12 years. Adhering to the active nutrition program for 60 days resulted in a mean weight loss of approximately 6.5 pounds, with a 2-pound weight gain noted for subjects in the usual care group. Related to this, reductions were noted in BMI (p < 0.001), percent fat (p = 0.017), and waist (4 cm, p < 0.001) and hip (3 cm, p < 0.001) circumferences for the active nutrition group but not usual care. Clinically relevant changes were noted for reductions in blood pressure (5 mm Hg) and triglycerides (12 mg/dL) for the active nutrition group. From a subjective perspective, participants in the active nutrition group reported improvements in their self-esteem, motivation, endurance, physical appearance, and strength (p < 0.001). The above was achieved without participants reporting any significant increase in hunger during the intervention, despite the expected reduction in calories.
conclusionAdhering to a semi-structured diet plan that allows for one "regular" whole-food meal daily is well-tolerated and enhances weight loss, physiological factors, and perceived wellness. Follow-up studies with a balanced representation of biological men and women are warranted to determine the longer-term impact of this nutrition program on weight loss and markers of metabolic health.
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