ArticleCureus2024
Bridging Neuroscience and Clinical Practice: Accelerating Stroke Recovery in a Pontine Infarction Case Through Neuroplasticity-Based Rehabilitation.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- A narrative review of motor control dual pathways: the corticospinal and reticulospinal tracts in synergy and differentiation.Frontiers in neuroanatomy · 2026Review
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Foundational neuroscience is crucial to locating lesions, understanding current functional limitations, making correct prognoses, and designing holistic and realistic treatment plans for stroke patients. A model bridging neuroscience knowledge and clinical practice was assessed through a rare pontine infarction case. A 76-year-old patient suffered two consecutive right-sided pontine ischemic strokes, leading to significant motor and sensory abnormalities on the left side. After the strokes stabilized, the patient was admitted to Knoxville Rehabilitation Hospital on August 10, 2023, under an intensive rehabilitation program grounded in neuroscience-based principles of plasticity. Remarkably, the patient fully recovered sensation by August 17. The clinical presentations, which included no ipsilateral cranial nerve dysfunction but the contralateral compromise of cranial nerves V and VII, indicated lesions in the right middle to caudal basilar pons. Employing available brainstem motor control systems, including reticulospinal and vestibulospinal tracts, the rehabilitation team designed a task-oriented, realistic neuroplasticity program to focus on gross motor skills such as postural control, bed mobility, transfers, walking, and stair negotiation, dynamically adjusted daily according to the patient's progress, while waiting for the recovery of corticospinal tract. The patient successfully improved from varied levels of assistance to independently performing all tasks except stair negotiation, which required supervision due to safety concerns, possibly resulting from past silent cerebrovascular problems. The patient was discharged home on August 29 after demonstrating significant functional recovery. This study highlights leveraging foundational neuroscience knowledge to accelerate recovery and quickly improve stroke rehabilitation outcomes.
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