Evidence map›Paper›PMID 39606466›Full record

ArticleResearch square2025

Detecting DNA Translocation through a Nanopore using a van der Waals Heterojunction Diode.

Sihan Chen, Siyuan Huang, Jangyup Son, Edmund Han, Kenji Watanabe, Takashi Taniguchi, Pinshane Y Huang, William P King, Arend M van der Zande, Rashid Bashir

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Sihan ChenHolonyak Micro and Nanotechnology Laboratory, The Grainger College of Engineering, University of Illinois Urbana-Champaign, Urbana, IL 61801, United States.
Siyuan HuangDepartment of Mechanical Science and Engineering, The Grainger College of Engineering, University of Illinois Urbana-Champaign, Urbana, IL 61801, United States.
Jangyup SonDepartment of Mechanical Science and Engineering, The Grainger College of Engineering, University of Illinois Urbana-Champaign, Urbana, IL 61801, United States.
Edmund HanDepartment of Materials Science and Engineering, The Grainger College of Engineering, University of Illinois Urbana-Champaign, Urbana, IL 61801, United States.
Kenji WatanabeResearch Center for Electronic and Optical Materials, National Institute for Materials Science, Tsukuba, Ibaraki 305-0044, Japan.ORCID https://orcid.org/0000-0003-3701-8119
Takashi TaniguchiResearch Center for Materials Nanoarchitectonics, National Institute for Materials Science, Tsukuba, Ibaraki 305-0044, Japan.ORCID https://orcid.org/0000-0002-1467-3105
Pinshane Y HuangDepartment of Materials Science and Engineering, The Grainger College of Engineering, University of Illinois Urbana-Champaign, Urbana, IL 61801, United States.ORCID https://orcid.org/0000-0002-1095-1833
William P KingHolonyak Micro and Nanotechnology Laboratory, The Grainger College of Engineering, University of Illinois Urbana-Champaign, Urbana, IL 61801, United States.
Arend M van der ZandeHolonyak Micro and Nanotechnology Laboratory, The Grainger College of Engineering, University of Illinois Urbana-Champaign, Urbana, IL 61801, United States.ORCID https://orcid.org/0000-0001-5104-9646
Rashid BashirHolonyak Micro and Nanotechnology Laboratory, The Grainger College of Engineering, University of Illinois Urbana-Champaign, Urbana, IL 61801, United States.

Funding

Atomically-thin diode integrated into a nanopore DNA SensorR21HG010701 · NHGRI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BASHIR, RASHID, VAN DER ZANDE, AREND · 2019 to 2020
$398k
NHGRI NIH HHS R21 HG010701
6 · The paper itself

Abstract

A long-unrealized goal in solid-state nanopore sensing is to achieve out-of-plane electrical sensing and control of DNA during translocation, which is a prerequisite for base-by-base ratcheting that enables DNA sequencing in biological nanopores. Two-dimensional (2D) heterostructures, with their capability to construct out-of-plane electronics with atomic layer precision, are ideal yet unexplored candidates for use as electrical sensing membranes. Here we demonstrate a nanopore architecture using a vertical 2D heterojunction diode consisting of p-type WSe

Indexed as

DNAion transportnanoporePhysical Sciences – Applied Physical Sciencessingle moleculevan der Waals heterojunction

Identifiers

PMID39606466
PMCPMC11601842

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.