Evidence map›Paper›PMID 39606462›Full record

ArticleResearch square2024

A Covalent Chemical Probe for

Anirban Ghoshal, Edwin G Tse, Mohammad Anwar Hossain, Kesatebrhan Haile Asressu, Eric M Merten, John D Sears, Stefanie Howell, Sumera Perveen, Jane Burdick, Noah L Morales and 17 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

27 authors.

Anirban GhoshalStructural Genomics Consortium, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Edwin G TseStructural Genomics Consortium, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID https://orcid.org/0000-0002-9133-9274
Mohammad Anwar HossainStructural Genomics Consortium, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Kesatebrhan Haile AsressuStructural Genomics Consortium, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Eric M MertenUNC Eshelman School of Pharmacy, Center for Integrative Chemical Biology and Drug Discovery, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
John D SearsDepartment of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Stefanie HowellStructural Genomics Consortium, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Sumera PerveenStructural Genomics Consortium, University of Toronto, Toronto, Ontario, M5G 1L7, Canada.ORCID https://orcid.org/0000-0002-8898-9540
Jane BurdickDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Noah L MoralesDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Sabian A MartinezDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Isabella LawDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Bennett J DavenportDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO 80045, USA.
Thomas E MorrisonDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO 80045, USA.
Zachary J StreblowVaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR, 97006, USA.
Daniel N StreblowVaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR, 97006, USA.
Angie L MordantUNC Metabolomics and Proteomics Core, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Thomas S WebbUNC Metabolomics and Proteomics Core, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Aurora CabreraUNC Metabolomics and Proteomics Core, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Laura E HerringUNC Metabolomics and Proteomics Core, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Cheryl H ArrowsmithStructural Genomics Consortium, University of Toronto, Toronto, Ontario, M5G 1L7, Canada.ORCID https://orcid.org/0000-0002-4971-3250
Kenneth H PearceUNC Eshelman School of Pharmacy, Center for Integrative Chemical Biology and Drug Discovery, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Nathaniel J MoormanDepartment of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Mark T HeiseDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Rafael Miguez CouñagoStructural Genomics Consortium, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Peter J BrownStructural Genomics Consortium, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID https://orcid.org/0000-0002-8454-0367
Timothy M WillsonStructural Genomics Consortium, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID https://orcid.org/0000-0003-4181-8223

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Deborah F. Tate · 1985 to 2026
$201.5M
Research Project 1: Coronavirus antiviral lead development and combination testingU19AI171292 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BARIC, RALPH S, WILLSON, TIMOTHY M · 2022 to 2022
$65.5M
Request for a 500 MHz NMR console and nitrogen-cooled cryoprobeS10OD032476 · OD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LEE, ANDREW L · 2022 to 2022
$599k
NCI NIH HHS P30 CA016086NIAID NIH HHS U19 AI171292NIH HHS S10 OD032476
6 · The paper itself

Abstract

RA-0003022 (

Identifiers

PMID39606462
PMCPMC11601817

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.