Evidence map›Paper›PMID 39606218›Full record

ArticleJACC. Advances2024

Electronic Nudge Letters to Increase Influenza Vaccination Uptake in Younger and Middle-Aged Individuals With Diabetes.

Mats C Højbjerg Lassen, Niklas Dyrby Johansen, Muthiah Vaduganathan, Ankeet S Bhatt, Daniel Modin, Safia Chatur, Brian L Claggett, Kira Hyldekær Janstrup, Carsten Schade Larsen, Lykke Larsen and 9 more

Registry-linked trialAbstract read
In one paragraph

Article in JACC. Advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06030739 (Nationwide Utilization of Danish Government Electronic Letter System for Increasing InFLUenza Vaccine Uptake Among Adults With Chronic Disease), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06030739 nacompletednot on this map

Nationwide Utilization of Danish Government Electronic Letter System for Increasing InFLUenza Vaccine Uptake Among Adults With Chronic Disease

TypeinterventionalSponsorTor Biering-SørensenRan2023 to 2024Enrolled299,881ConditionsInfluenza, Behavior and Behavior MechanismsArmsBehavioral Economic Principles
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Mats C Højbjerg LassenDepartment of Cardiology, Copenhagen University Hospital-Herlev and Gentofte, Copenhagen, Denmark.
Niklas Dyrby JohansenDepartment of Cardiology, Copenhagen University Hospital-Herlev and Gentofte, Copenhagen, Denmark.
Muthiah VaduganathanCardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Ankeet S BhattKaiser Permanente San Francisco Medical Center & Division of Research, San Francisco, California, USA.
Daniel ModinDepartment of Cardiology, Copenhagen University Hospital-Herlev and Gentofte, Copenhagen, Denmark.
Safia ChaturCardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Brian L ClaggettCardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Kira Hyldekær JanstrupDepartment of Cardiology, Copenhagen University Hospital-Herlev and Gentofte, Copenhagen, Denmark.
Carsten Schade LarsenDepartment of Clinical Medicine-Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark.
Lykke LarsenResearch Unit for Infectious Diseases, Odense University Hospital, Odense, Denmark.
Lothar WieseDepartment of Infectious Diseases, Zealand University Hospital, Roskilde, Denmark.
Michael Dalager-PedersenDepartment of Infectious Diseases, Aalborg University Hospital, Aalborg, Denmark.
Lars KøberDepartment of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.
Scott D SolomonCardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Pradeesh SivapalanDepartment of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.
Jens Ulrik Stæhr JensenDepartment of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.
Cyril Jean-Marie MartelEpidemiological Infectious Disease Preparedness, Statens Serum Institut, Copenhagen, Denmark.
Tyra Grove KrauseEpidemiological Infectious Disease Preparedness, Statens Serum Institut, Copenhagen, Denmark.
Tor Biering-SørensenDepartment of Cardiology, Copenhagen University Hospital-Herlev and Gentofte, Copenhagen, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Despite evidence demonstrating that influenza vaccination is associated with reduced risk of cardiovascular events and all-cause mortality in individuals with diabetes mellitus (DM), vaccine uptake remains suboptimal. Objectives: The purpose of this study was to assess the effectiveness of electronically delivered nudges on influenza vaccine uptake according to the presence of DM status versus other chronic diseases. Methods: NUDGE-FLU-CHRONIC was a nationwide, randomized, pragmatic implementation trial among younger and middle-aged (18-64 years) Danish citizens with chronic disease during the 2023/2024 influenza season. Participants were randomized in a 2.45:1:1:1:1:1:1 ratio to usual care (no electronic letter) or 1 of 6 different electronic nudge letters. The endpoint was receipt of a seasonal influenza vaccine on or before January 1, 2024. Results: Of 299,881 participants, 57,666 (19.2%) had DM (median age: 51.6 years, 43.0% female). During the season, 43.0% of those with DM vs 34.6% of those without DM received the vaccine ( Conclusions: Electronic nudge letters effectively boosted vaccine uptake in individuals with DM and in individuals free of DM but with other chronic diseases, but the effect was lower among those with DM. Electronic nudges represent a low-cost and effective strategy to boost influenza vaccination rates in the DM population. (Nationwide Utilization of Danish Government Electronic Letter System for Increasing InFLUenza Vaccine Uptake Among Adults With Chronic Disease; NCT06030739).

Indexed as

behavioral sciencediabetesimplementationinfluenzanudgingrandomized controlled trialregistryvaccination

Identifiers

PMID39606218
PMCPMC11600668

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.