Evidence map›Paper›PMID 39606133›Full record

ArticleCureus2024

Calciphylaxis in a Patient on Hemodialysis: A Case Report.

Yahia Metwally, Hashim Abbas, Vishnu Jeyalan, Amjad Khanfar

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yahia MetwallyNephrology, Manchester University NHS Foundation Trust, Manchester, GBR.
Hashim AbbasNephrology, Manchester University NHS Foundation Trust, Manchester, GBR.
Vishnu JeyalanNephrology, Manchester University NHS Foundation Trust, Manchester, GBR.
Amjad KhanfarCardiology, Manchester University NHS Foundation Trust, Manchester, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calciphylaxis is a rare but life-threatening complication of end-stage renal disease (ESRD), most often seen in patients undergoing hemodialysis. This condition is driven by calcium deposition in small blood vessels, leading to restricted blood flow, tissue ischemia, and often severe pain. While calciphylaxis typically affects areas with increased adiposity, such as the abdomen and proximal extremities, it can manifest on any skin surface, including rare sites like the genital region. Managing calciphylaxis is particularly challenging due to its rapid progression and limited treatment options. We report the case of a 53-year-old man with ESRD caused by long-standing diabetes, who developed painful necrotic lesions on the glans penis. Despite early diagnosis and treatment with sodium thiosulfate, his condition rapidly worsened. This case highlights the devastating progression of penile calciphylaxis and the complexities of managing such a rare presentation.

Indexed as

calciphylaxisckdend stage renal disease (esrd)hemodialysispenile calciphylaxisserious complication of hemodialysissodium thiosulfateuremic calciphylaxiswarfarin-induced calciphyalxis

Identifiers

PMID39606133
PMCPMC11600236

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.