Evidence map›Paper›PMID 39606118›Full record

ArticleFrontiers in microbiology2024

Utilizing metagenomic next-generation sequencing and phylogenetic analysis to identify a rare pediatric case of

Liangkang Lin, Lili Luo, Mei Wu, Jun Chen, Yi Liao, Haiyang Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Global Review onInfectious disease reports · 2026
    Review
  2. Article
  3. Journal of clinical medicine · 2025
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Liangkang Lin *Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.
Lili Luo *Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.
Mei WuDepartment of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.
Jun ChenDepartment of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.
Yi LiaoKey Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, Chengdu, China.
Haiyang ZhangDepartment of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: Diagnosis was confirmed via metagenomic next-generation sequencing (mNGS) of both blood and cerebrospinal fluid (CSF). This analysis not only substantiated the infection but also revealed a potential new genotype of Results: Immediate treatment with Amphotericin B (Am B) and rifampin was initiated upon diagnosis. Despite aggressive management and supportive care, the patient failed to maintain hemodynamic stability, continued to show a decrease in cardiac output, and exhibited relentless progression of central nervous system failure, culminating in death within 72 h. Conclusion: Our report documents a rare pediatric case of

Indexed as

fulminant myocarditismetagenomic next-generation sequencingNaegleria fowleriphylogenetic analysisprimary amoebic meningoencephalitis

Identifiers

PMID39606118
PMCPMC11599265

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.