Evidence map›Paper›PMID 39605880›Full record

ArticleJBMR plus2024

Therapy with transitions from one bone-forming agent to another: a retrospective cohort study on teriparatide and romosozumab.

Tomonori Kobayakawa, Yasuhide Kanayama, Yuji Hirano, Toshitaka Yukishima, Yukio Nakamura

Abstract read
In one paragraph

Article in JBMR plus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Sequential and Long-term Therapy for Osteoporosis.Current osteoporosis reports · 2025
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tomonori KobayakawaKobayakawa Orthopedic and Rheumatologic Clinic, Fukuroi 437-0061, Shizuoka, Japan.
Yasuhide KanayamaDepartment of Orthopedic Surgery and Rheumatology, Toyota Kosei Hospital, Toyota 470-0396, Aichi, Japan.
Yuji HiranoDepartment of Rheumatology, Toyohashi Municipal Hospital, Toyohashi 441-8570, Aichi, Japan.
Toshitaka YukishimaKobayakawa Orthopedic and Rheumatologic Clinic, Fukuroi 437-0061, Shizuoka, Japan.ORCID https://orcid.org/0000-0003-2265-6724
Yukio NakamuraDepartment of Orthopedic Surgery, Division of Osteoporosis, Locomotive Syndrome, Joint Disease Center, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi 480-1195, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate the effectiveness of sequential therapy with a bone formation-promoting agent (either teriparatide or romosozumab) for osteoporosis treatment following prior treatment with the other bone-forming agent (teriparatide or romosozumab). This is a multicenter retrospective cohort study observing 2 groups for comparison: one with 69 patients transitioning from teriparatide to romosozumab (the T2R group) and the other with 25 patients transitioning from romosozumab to teriparatide (the R2T group), monitored for 12 months on the second drug. Key outcomes included changes in bone mineral density (BMD), bone turnover marker changes, and adverse events. The mean ages of each group were 72.3 years in the T2R group and 67.6 years in the R2T group, with the proportions of women being 91.3% and 80.0%, respectively. The percent changes of BMD in the lumbar spine after 12 months of sequential therapy were +10.8% in the T2R group (

Indexed as

bone modeling and remodelingosteoporosisromosozumabsequential therapyteriparatide

Identifiers

PMID39605880
PMCPMC11601723

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.