Evidence map›Paper›PMID 39605672›Full record

ArticlebioRxiv : the preprint server for biology2025

Quantitative mapping of cerebrovascular reactivity amplitude and delay with breath-hold BOLD fMRI when end-tidal CO

Rebecca G Clements, Kristina M Zvolanek, Neha A Reddy, Kimberly J Hemmerling, Roza G Bayrak, Catie Chang, Molly G Bright

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Rebecca G ClementsDepartment of Physical Therapy and Human Movement Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.ORCID 0000-0002-4787-1124
Kristina M ZvolanekDepartment of Physical Therapy and Human Movement Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.ORCID 0000-0003-2239-7902
Neha A ReddyDepartment of Physical Therapy and Human Movement Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.ORCID 0000-0001-8938-540X
Kimberly J HemmerlingDepartment of Physical Therapy and Human Movement Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.ORCID 0000-0001-9913-492X
Roza G BayrakDepartment of Electrical and Computer Engineering, Vanderbilt University, Nashville, TN, USA.ORCID 0000-0002-7197-1248
Catie ChangDepartment of Electrical and Computer Engineering, Vanderbilt University, Nashville, TN, USA.ORCID 0000-0003-1541-9579
Molly G BrightDepartment of Physical Therapy and Human Movement Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.ORCID 0000-0001-7257-9646

Funding

Graduate Training Program for Magnetic Resonance ImagingT32EB025766 · NIBIB · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Michael Markl · 2019 to 2026
$1.6M
Probing silent cerebral infarct pathogenesis in sickle cell disease with cerebrovascular MRIF31HL166079 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ZVOLANEK, KRISTINA · 2022 to 2024
$129k
Probing an increased reliance on reticulospinal motor pathways in chronic hemiparetic stroke with advanced spinal cord functional MRIF31NS134222 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HEMMERLING, KIMBERLY JIYUN · 2023 to 2024
$89k
NHLBI NIH HHS F31 HL166079NIBIB NIH HHS T32 EB025766NINDS NIH HHS F31 NS134222
6 · The paper itself

Abstract

Cerebrovascular reactivity (CVR), the ability of cerebral blood vessels to dilate or constrict in response to a vasoactive stimulus, is a clinically useful measure of cerebrovascular health. CVR is often measured using a breath-hold task to modulate blood CO

Indexed as

BOLD fMRIbreath-hold taskcerebrovascular reactivityCO2deep learningrespiration volume per time

Identifiers

PMID39605672
PMCPMC11601616

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.