Evidence map›Paper›PMID 39605631›Full record

ArticlebioRxiv : the preprint server for biology2024

Aberrant expression of collagen type X in solid tumor stroma is associated with EMT, immunosuppressive and pro-metastatic pathways, bone marrow stromal cell signatures, and poor survival prognosis.

Elliot H H Famili-Youth, Aryana Famili-Youth, Dongfang Yang, Ayesha Siddique, Elizabeth Y Wu, Wenguang Liu, Murray B Resnick, Qian Chen, Alexander S Brodsky

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Elliot H H Famili-YouthMedical Scientist Training Program, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID 0000-0002-9866-3747
Aryana Famili-YouthMedical Scientist Training Program, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID 0000-0002-1598-348X
Dongfang YangDepartment of Pathology and Laboratory Medicine, Rhode Island Hospital and Lifespan Medical Center, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Ayesha SiddiqueDepartment of Pathology and Laboratory Medicine, Rhode Island Hospital and Lifespan Medical Center, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Elizabeth Y WuDepartment of Pathology and Laboratory Medicine, Rhode Island Hospital and Lifespan Medical Center, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Wenguang LiuDepartment of Orthopedics, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Murray B ResnickDepartment of Pathology and Laboratory Medicine, Rhode Island Hospital and Lifespan Medical Center, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Qian ChenDepartment of Orthopedics, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Alexander S BrodskyDepartment of Pathology and Laboratory Medicine, Rhode Island Hospital and Lifespan Medical Center, Warren Alpert Medical School of Brown University, Providence, RI, USA.

Funding

Pilot Projects ProgramP30GM122732 · NIGMS · RHODE ISLAND HOSPITAL · PI CRISCO, JOSEPH J · 2017 to 2021
$6.6M
Single-Cell Transposon Activation in the CNS during AD Progression: Sex-dependent MechanismsR01AG080141 · NIA · RHODE ISLAND HOSPITAL · PI QIAN CHEN · 2023 to 2026
$2.9M
NIA NIH HHS R01 AG080141NIGMS NIH HHS P30 GM122732
6 · The paper itself

Abstract

Background: Collagen type X (ColXα1, encoded by Methods: Immunohistochemistry was performed to examine collagen type X expression in solid tumors. WGCNA was used to generate Results: Expression of Conclusions:

Indexed as

breast cancercollagen type Xosteoarthritispancreatic cancertumor microenvironment

Identifiers

PMID39605631
PMCPMC11601388

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.