Evidence map›Paper›PMID 39605594›Full record

ArticlebioRxiv : the preprint server for biology2024

Precision-cut lung slices in air-liquid interface (PCLS-ALI): A novel

L E Gonzales-Huerta, T J Williams, R Aljohani, B D Robertson, C A Evans, Dph Armstrong-James

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

L E Gonzales-HuertaDepartment of Infectious Disease, Imperial College London, SW7 2AZ, UK.ORCID 0000-0003-3736-6850
T J WilliamsDepartment of Infectious Disease, Imperial College London, SW7 2AZ, UK.ORCID 0000-0002-1201-2944
R AljohaniDepartment of Infectious Disease, Imperial College London, SW7 2AZ, UK.ORCID 0000-0002-1648-3946
B D RobertsonDepartment of Infectious Disease, Imperial College London, SW7 2AZ, UK.ORCID 0000-0001-5785-5307
C A EvansDepartment of Infectious Disease, Imperial College London, SW7 2AZ, UK.ORCID 0000-0002-6873-5447
Dph Armstrong-JamesDepartment of Infectious Disease, Imperial College London, SW7 2AZ, UK.ORCID 0000-0002-1014-7343

Funding

Infectious Diseases Training program in Bolivia: South-South Training with PeruD43TW010074 · FIC · JOHNS HOPKINS UNIVERSITY · PI ROBERT H GILMAN, Jeffrey Tornheim · 2015 to 2026
$3.5M
FIC NIH HHS D43 TW010074Wellcome Trust
6 · The paper itself

Abstract

Pulmonary Aspergillosis is a respiratory infection with a high mortality rate, which affects patients with immunosuppression or structural lung defects. Antifungal treatment options are few and many have narrow therapeutic margins and potentially serious side effects. In recent years, there are growing numbers of reports of antifungal resistance. Thus, there is an urgent need for effective models to study fungal pathogenesis and test antifungal therapies in the respiratory system. Here, we present a novel

Indexed as

3Rs principlesair-liquid interfaceALIantifungalsAspergillus fumigatusinnate immunityPCLSPrecision-cut lung slicesPulmonary Aspergillosis

Identifiers

PMID39605594
PMCPMC11601337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.