Evidence map›Paper›PMID 39605520›Full record

ArticlebioRxiv : the preprint server for biology2024

Sugar phosphate-mediated inhibition of peptidoglycan precursor synthesis.

Megan R Keller, Vijay Soni, Megan Brown, Kelly M Rosch, Anas Saleh, Kyu Rhee, Tobias Doerr

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Megan R KellerWeill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853, USA.
Vijay SoniDepartment of Medicine, Division of Infectious Diseases, Weill Cornell Medicine, New York, NY 10021.ORCID 0000-0002-3395-7429
Megan BrownDepartment of Medicine, Division of Infectious Diseases, Weill Cornell Medicine, New York, NY 10021.
Kelly M RoschWeill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853, USA.
Anas SalehDepartment of Medicine, Division of Infectious Diseases, Weill Cornell Medicine, New York, NY 10021.
Kyu RheeCornell Institute of Host-Microbe Interactions and Disease, Cornell University, Ithaca NY 14853, USA.
Tobias DoerrWeill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0003-3283-9161

Funding

Tri-I Training Program in MetabolomicsR25AI140472 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI Kyu Y Rhee · 2019 to 2026
$2.4M
Cell envelope stress responses and the mechanism of antibiotic tolerance in Gram-negative pathogensR01AI143704 · NIAID · CORNELL UNIVERSITY · PI DOERR, TOBIAS · 2019 to 2023
$2.0M
The mechanism of autolysin regulation in Vibrio choleraeR01GM130971 · NIGMS · CORNELL UNIVERSITY · PI DOERR, TOBIAS · 2019 to 2025
$2.0M
Host-Microbe Interactions that Determine Host Traits and DiseaseT32AI145821 · NIAID · CORNELL UNIVERSITY · PI LAZZARO, BRIAN · 2020 to 2024
$1.9M
NIAID NIH HHS R01 AI143704NIAID NIH HHS R25 AI140472NIAID NIH HHS T32 AI145821NIGMS NIH HHS R01 GM130971
6 · The paper itself

Abstract

Antibiotic tolerance, the widespread ability of diverse pathogenic bacteria to sustain viability in the presence of typically bactericidal antibiotics for extended time periods, is an understudied steppingstone towards antibiotic resistance. The Gram-negative pathogen

Indexed as

antibiotic resistancebacterial metabolismenzyme inhibitorGram-negative bacteriastress

Identifiers

PMID39605520
PMCPMC11601392

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.