Evidence map›Paper›PMID 39605518›Full record

ArticlebioRxiv : the preprint server for biology2024

Multiscale Cloud-Based Pipeline for Neuronal Electrophysiology Analysis and Visualization.

Jinghui Geng, Kateryna Voitiuk, David F Parks, Ash Robbins, Alex Spaeth, Jessica L Sevetson, Sebastian Hernandez, Hunter E Schweiger, John P Andrews, Spencer T Seiler and 9 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Jinghui GengDepartment of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA.ORCID 0000-0002-3431-9568
Kateryna VoitiukDepartment of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA.ORCID 0000-0002-6392-5188
David F ParksDepartment of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA.ORCID 0000-0002-4635-8206
Ash RobbinsDepartment of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA.ORCID 0000-0002-5556-8547
Alex SpaethDepartment of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA.ORCID 0000-0003-0702-3945
Jessica L SevetsonDepartment of Molecular, Cell, and Developmental Biology, University of California Santa Cruz, Santa Cruz, CA 95064, USA.ORCID 0000-0001-7434-1447
Sebastian HernandezDepartment of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA.ORCID 0009-0000-8811-8596
Hunter E SchweigerDepartment of Molecular, Cell, and Developmental Biology, University of California Santa Cruz, Santa Cruz, CA 95064, USA.ORCID 0000-0003-0399-9481
John P AndrewsDepartment of Neurological Surgery, University of California San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0002-8025-1525
Spencer T SeilerDepartment of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA.ORCID 0000-0002-0087-1346
Matthew A T ElliottDepartment of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA.ORCID 0000-0001-6313-6819
Edward F ChangDepartment of Neurological Surgery, University of California San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0003-2480-4700
Tomasz J NowakowskiDepartment of Neurological Surgery, University of California San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0003-2345-4964
Rob CurrieGenomics Institute, University of California Santa Cruz, Santa Cruz, CA 95064, USA.ORCID 0000-0003-1828-1827
Mohammed A Mostajo-RadjiGenomics Institute, University of California Santa Cruz, Santa Cruz, CA 95064, USA.ORCID 0000-0002-1634-7514
David HausslerDepartment of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA.ORCID 0000-0003-1533-4575
Tal SharfDepartment of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA.ORCID 0000-0002-7899-2818
Sofie R SalamaDepartment of Molecular, Cell, and Developmental Biology, University of California Santa Cruz, Santa Cruz, CA 95064, USA.ORCID 0000-0001-6999-7193
Mircea TeodorescuDepartment of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA.ORCID 0000-0001-7085-5248

Funding

Nanoparticle Tracking Analyzer (NTA) for the Center for Live Cell GenomicsRM1HG011543 · NHGRI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI HAUSSLER, DAVID H, SALAMA, SOFIE REDA · 2021 to 2025
$12.0M
Data Resource and Administrative Coordination Center for the Scalable and Systematic Neurobiology of Psychiatric and Neurodevelopmental Disorder Risk Genes ConsortiumU24MH132628 · NIMH · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI DAVID H HAUSSLER, Tomasz Nowakowski · 2023 to 2026
$7.9M
IRACDA at UCSC and CSUMBK12GM139185 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI FORSBERG, CAMILLA, HINCK, LINDSAY E · 2020 to 2024
$4.1M
Dissecting the role of NOTCH2NL genes in human brain development and neurological disorders associated with chromosome 1q21.1 distal duplications and deletions.R01MH120295 · NIMH · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI SALAMA, SOFIE REDA · 2020 to 2024
$3.7M
NHGRI NIH HHS RM1 HG011543NIGMS NIH HHS K12 GM139185NIMH NIH HHS R01 MH120295NIMH NIH HHS U24 MH132628
6 · The paper itself

Abstract

Electrophysiology offers a high-resolution method for real-time measurement of neural activity. Longitudinal recordings from high-density microelectrode arrays (HD-MEAs) can be of considerable size for local storage and of substantial complexity for extracting neural features and network dynamics. Analysis is often demanding due to the need for multiple software tools with different runtime dependencies. To address these challenges, we developed an open-source cloud-based pipeline to store, analyze, and visualize neuronal electrophysiology recordings from HD-MEAs. This pipeline is dependency agnostic by utilizing cloud storage, cloud computing resources, and an Internet of Things messaging protocol. We containerized the services and algorithms to serve as scalable and flexible building blocks within the pipeline. In this paper, we applied this pipeline on two types of cultures, cortical organoids and

Indexed as

cloud computingcontainerizationdata pipelineelectrophysiology recording analysisInternet of Thingsmicroelectrode arraysneuronal cultures

Identifiers

PMID39605518
PMCPMC11601321

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.