Evidence map›Paper›PMID 39605188›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Negative Pressure Smart Patch to Sense and Heal the Wound.

Xing Liu, Peng Zhao, Xiaozhuo Wu, Yawei Zhao, Feifan Zhou, Ying Luo, Xiaoli Jia, Wen Zhong, Malcolm Xing, Guozhong Lyu

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Negative pressure wound therapy for the prevention of surgical site infections in orthopedic and trauma surgery: a systematic review and meta-analysis of RCTs.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2025
    Pooled it
  2. Review
  3. Article
  4. Article
  5. [Research advances in three-dimensional bioprinted wound dressings].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025
    Review
  6. Article
  7. Article
  8. Negative Pressure Smart Patch to Sense and Heal the Wound.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xing LiuEngineering Research Center of the Ministry of Education for Wound Repair Technology, Jiangnan University, Affiliated Hospital of Jiangnan University, Wuxi, 214000, China.
Peng ZhaoEngineering Research Center of the Ministry of Education for Wound Repair Technology, Jiangnan University, Affiliated Hospital of Jiangnan University, Wuxi, 214000, China.
Xiaozhuo WuDepartment of Mechanical Engineering, University of Manitoba, Winnipeg, R3T 2N2, Canada.
Yawei ZhaoDepartment of Biosystems Engineering, University of Manitoba, Winnipeg, R3T 2N2, Canada.
Feifan ZhouEngineering Research Center of the Ministry of Education for Wound Repair Technology, Jiangnan University, Affiliated Hospital of Jiangnan University, Wuxi, 214000, China.
Ying LuoEngineering Research Center of the Ministry of Education for Wound Repair Technology, Jiangnan University, Affiliated Hospital of Jiangnan University, Wuxi, 214000, China.
Xiaoli JiaEngineering Research Center of the Ministry of Education for Wound Repair Technology, Jiangnan University, Affiliated Hospital of Jiangnan University, Wuxi, 214000, China.
Wen ZhongDepartment of Biosystems Engineering, University of Manitoba, Winnipeg, R3T 2N2, Canada.
Malcolm XingDepartment of Mechanical Engineering, University of Manitoba, Winnipeg, R3T 2N2, Canada.ORCID 0000-0002-3547-0462
Guozhong LyuEngineering Research Center of the Ministry of Education for Wound Repair Technology, Jiangnan University, Affiliated Hospital of Jiangnan University, Wuxi, 214000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Negative pressure wound therapy (NPWT) offers significant advantages in terms of rate and time for healing through generating sub-vacuum to draw out inflammatory exudate and promote wound closure. However, continuous drainage probably leads to healing delay due to the lack of information about the real status of the wound bed and the potential risk of infection. To address this concern, printed Negative Pressure Smart Patch (NPSP) is reported by integrating smart real-time sensing acidity (infection) and glucose, and anti-infection into NPWT systems. In addition, NPSP delivers vancomycin through chitosan porous microspheres under negative pressure to modulate wound healing. Compared with NPWT, NPSP projects a promising approach to removing bacteria, reducing local inflammation, and accelerating healing in a short period of time.

Indexed as

Negative-Pressure Wound TherapyWound HealingAnimalsAnti-Bacterial AgentsHumansVancomycinAnti-Bacterial AgentsVancomycindrug deliveryglucose‐sensingmicrospherespH‐sensingwound monitoring

Identifiers

PMID39605188
PMCPMC11744653

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.