Evidence map›Paper›PMID 39605013›Full record

ArticleBMC urology2024

Body mass index and penile cancer incidence: results from a Norwegian cohort study of 829,081 men.

Dagfinn Aune, Marie Nordsletten, Tor Åge Myklebust, Trude Eid Robsahm, Bjørn Steen Skålhegg, Tom Mala, Sheraz Yaqub, Usman Saeed

Abstract read
In one paragraph

Article in BMC urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dagfinn AuneDepartment of Research, Cancer Registry of Norway, Norwegian Institute of Public Health, Oslo, Norway. d.aune@imperial.ac.uk.
Marie NordslettenDepartment of Gastrointestinal and Paediatric Surgery, Oslo University Hospital, Oslo, Norway.
Tor Åge MyklebustDepartment of Registration, Cancer Registry of Norway, Norwegian Institute of Public Health, Oslo, Norway.
Trude Eid RobsahmDepartment of Research, Cancer Registry of Norway, Norwegian Institute of Public Health, Oslo, Norway.
Bjørn Steen SkålheggDivision for Molecular Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Tom MalaDepartment of Gastrointestinal and Paediatric Surgery, Oslo University Hospital, Oslo, Norway.
Sheraz YaqubDepartment of Gastrointestinal and Paediatric Surgery, Oslo University Hospital, Oslo, Norway.
Usman SaeedDepartment of Gastrointestinal and Paediatric Surgery, Oslo University Hospital, Oslo, Norway.

Funding

World Cancer Research Fund International WCRF 2020/035
6 · The paper itself

Abstract

backgroundA few previous studies have suggested a possible association between adiposity and increased risk of penile cancer, however, the evidence is to date limited for this rare cancer. We investigated the association between body mass index (BMI) and penile cancer risk in a large Norwegian cohort.

methodsThe analyses included 829,081 men aged 16-75 years at baseline in 1963-1975. Multivariable Cox regression analyses were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for the associations between BMI and penile cancer incidence.

resultsA total of 725 incident penile cancer cases occurred during 25.6 million person-years of follow-up. Compared to men with BMI 18.5-<25, the HRs (95% CIs) of those with a BMI of 15-<18.5, 25-<30, and ≥ 30 were 0.45 (0.15-1.41), 1.14 (0.97-1.33) and 1.63 (1.20-2.22), respectively, and the HR was 1.26 (1.12-1.42) per 5 kg/m

conclusionHigh BMI is associated with increased risk of penile cancer. Further studies are needed to investigate the potential underlying mechanisms.

Indexed as

Body Mass IndexPenile NeoplasmsAdolescentAdultAgedCohort StudiesHumansIncidenceMaleMiddle AgedNorwayObesityRisk FactorsYoung AdultBody mass indexcohortpenile cancer

Identifiers

PMID39605013
PMCPMC11603744

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.