ArticleBMC public health2024
The impact of early adversity on later life health, lifestyle, and cognition.
Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Cognitive impairment and dementia-Are they linked to childhood health and socioeconomic status? A systematic review.PloS one · 2025Pooled it
- Aging and resilience in Vietnamese American older adults: Evidence from the Vietnamese Insights into Cognitive Aging Program.International psychogeriatrics · 2026Article
- Associations between early-life adversity, coping strategies, and adult mental health, brain, and cognition.Scientific reports · 2026Article
- Childhood adversities and the exposome in dementia risk and brain health.Current opinion in psychiatry · 2026Review
- Associations of war-related exposures and early life adversity with late-life cognition.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Adrenarche as a regulator of sensitivity to early adversity.Journal of neuroendocrinology · 2026Review
- A history of maternal separation drives systemic aging-associated signatures in middle-aged male rats.Frontiers in cellular neuroscience · 2026Article
- Article
- Biological Mechanisms Linking Social Adversity and Cognition.Public health reviews · 2025Review
- Association between fetal exposure to the Chinese famine and cognitive decline in adulthood: a retrospective cohort study.Frontiers in nutrition · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundEarly life adversity has been shown to have long-lasting detrimental effects on a variety of biopsychosocial outcomes. Early adversity and its consequences may directly or indirectly affect cognitive aging and increase the risk of developing dementia in older age. Investigating the biopsychosocial outcomes associated with early adverse experiences is essential to inform health policies and promote healthy cognitive development across the life course.
methodsThe aim of this study is to investigate the effect of early adversity (i.e., abuse and deprivation) on selected outcomes (i.e., physical and mental health, lifestyle, and cognition) in two UK cohorts (the English Longitudinal Study of Ageing (ELSA), N = 12,653, Mdn
resultsMost of the results show that early adversity is negatively associated with health (both physical and mental), lifestyle, and cognition while also highlighting the important mediating role of education. However, differences exist according to the specific adversity experienced and the cohort studied.
conclusionsThe results found bring into attention the complex associations between early adversity and multiple later life outcomes, and suggest that various mechanisms might be at play. Furthermore, the findings highlight the importance of multi-cohort comparisons for the generalization of the results.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.