Evidence map›Paper›PMID 39604921›Full record

ArticleBMC ophthalmology2024

Optic neuropathy as an initial manifestation of acute retinal necrosis caused by varicella zoster virus: a case report.

Lili Li, Qiuxin Wu, Qingmei Tian, Guanyu Han, Xiaofeng Xie

Abstract readCase Reports
In one paragraph

Article in BMC ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lili LiAffiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, 250002, China.
Qiuxin WuAffiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, 250002, China.
Qingmei TianAffiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, 250002, China.
Guanyu HanShandong Academy of Eye Disease Prevention and Therapy, Jinan, Shandong, 250002, China.
Xiaofeng XieAffiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, 250002, China. yankeboshi@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe present the treatment and follow-up of a rare patient with acute retinal necrosis (ARN) with optic neuropathy as the first manifestation. CASE PRESENTATION: A 57-year-old male patient first presented with reduced vision and optic neuropathy in his right eye.After 20 days, the vision in the left eye decreased, and the slit-lamp examination showed no remarkable changes in the anterior segment. The right eye showed 2 + cells and flares in the anterior chamber. The iris texture was good, the pupils were round (light reflex), the crystalline lens was slightly opaque, and the vitreous was turbid. An anterior chamber paracentesis was performed to collect aqueous humor for polymerase chain reaction testing. The PCR test showed positive detection of VZV in the right eye, while the content of VZV in the left eye was lower than the reference value. Both eyes of the patient were successively diagnosed with acute retinal necrosis (ARN) due to VZV infection. The patient was treated with topical antiviral and anti-inflammatory eye medication, oral steroids, and general antiviral drugs. After three months, the vision and condition were relatively stable.

conclusionsClinicians should realize that accurate diagnosis and timely antiviral therapy are crucial for treating ARN.

Indexed as

Antiviral AgentsEye Infections, ViralHerpesvirus 3, HumanOptic Nerve DiseasesRetinal Necrosis Syndrome, AcuteHerpes Zoster OphthalmicusHumansMaleMiddle AgedVaricella Zoster Virus InfectionVisual AcuityAntiviral AgentsAcute retinal necrosisAntiviral treatmentOptic neuropathySteroidsVirus

Identifiers

PMID39604921
PMCPMC11603943

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.