Evidence map›Paper›PMID 39604769›Full record

Observational studyWorld journal of pediatrics : WJP2024

Nonspecific increase of αβTCR

Kuanysh Dossybayeva, Gulsamal Zhubanova, Assel Mussayeva, Zaure Mukusheva, Aiken Dildabayeva, Galiya Nauryzbayeva, Lyudmila Akhmaltdinova, Ulbolsyn Orumbayeva, Matthew Tanko, Dimitri Poddighe

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in World journal of pediatrics : WJP, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. (TCRαβCells · 2025
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kuanysh DossybayevaDepartment of Medicine, Nazarbayev University School of Medicine (NUSOM), 010000, Astana, Kazakhstan.
Gulsamal ZhubanovaDepartment of Medicine, Nazarbayev University School of Medicine (NUSOM), 010000, Astana, Kazakhstan.
Assel MussayevaDepartment of Medicine, Nazarbayev University School of Medicine (NUSOM), 010000, Astana, Kazakhstan.
Zaure MukushevaProgram of Pediatric Rheumatology, Clinical Academic Department of Pediatrics, University Medical Center, Astana, Kazakhstan.
Aiken DildabayevaProgram of Pediatric Rheumatology, Clinical Academic Department of Pediatrics, University Medical Center, Astana, Kazakhstan.
Galiya NauryzbayevaClinical Academic Department of Laboratory Medicine, Pathology and Genetics, Republican Diagnostic Center, University Medical Center, Astana, Kazakhstan.
Lyudmila AkhmaltdinovaClinical Academic Department of Pediatrics, National Research Center for Maternal and Child Health (NRCMCH), University Medical Center(UMC), 010000, Astana, Kazakhstan.
Ulbolsyn OrumbayevaClinical Academic Department of Laboratory Medicine, Pathology and Genetics, Republican Diagnostic Center, University Medical Center, Astana, Kazakhstan.
Matthew TankoDepartment of Medicine, Nazarbayev University School of Medicine (NUSOM), 010000, Astana, Kazakhstan.
Dimitri PoddigheDepartment of Medicine, Nazarbayev University School of Medicine (NUSOM), 010000, Astana, Kazakhstan. dimimedpv@yahoo.it.ORCID 0000-0001-6431-9334

Funding

Ministry of Education and Science of the Republic of Kazakhstan AP19677323Nazarbayev University 20122022CRP1604
6 · The paper itself

Abstract

backgroundAn increased number of double-negative T (DNT) cells expressing the αβ T cell receptor (αβ

methodsIn this cross-sectional, prospective, and observational study, children with rheumatic disorders and healthy controls were recruited to analyze the quantity and characteristics of circulating DNT cells using flow cytometry.

resultsOverall, the two study groups did not differ in their total DNT cell pool in the bloodstream. However, the number of αβ

conclusionsThese preliminary results indicate that circulating αβ

Indexed as

Flow CytometryReceptors, Antigen, T-Cell, alpha-betaRheumatic DiseasesAdolescentCase-Control StudiesChildChild, PreschoolCross-Sectional StudiesFemaleHumansMaleProspective StudiesT-LymphocytesReceptors, Antigen, T-Cell, alpha-betaDNT cellsDouble-negative T cellsJuvenile idiopathic arthritisPediatric rheumatic disordersSystemic lupus erythematosus

Identifiers

PMID39604769
PMCPMC11634929

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.