Evidence map›Paper›PMID 39604743›Full record

SynthesisClinical rheumatology2025

Global research trends of MicroRNAs in rheumatoid arthritis: bibliometrics and visualization analysis.

Xue Pang, Fengxia Xu, Chang Fan, Hui Jiang

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Clinical rheumatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xue PangClinical Research Experiment Center, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, 230012, Anhui, China.
Fengxia XuClinical Research Experiment Center, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, 230012, Anhui, China.
Chang FanClinical Research Experiment Center, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, 230012, Anhui, China.
Hui JiangClinical Research Experiment Center, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, 230012, Anhui, China. jianghui@ahtcm.edu.cn.ORCID http://orcid.org/0000-0002-4198-4507

Funding

Natural Science Foundation of Anhui Province 2208085MH276
6 · The paper itself

Abstract

backgroundRheumatoid arthritis (RA) is a chronic autoimmune disorder, and a growing body of research has demonstrated the involvement and regulatory roles of microRNAs (miRNAs) in the pathogenesis of RA. Consequently, this study aims to evaluate the current status and emerging trends in miRNA research related to RA by employing bibliometric analyses from a comprehensive perspective.

methodsRelevant literature pertaining to miRNA-related RA was systematically searched and screened from the Web of Science Core Collection (WOSCC) database, covering the period from January 1, 2010 to June 30, 2024. Subsequently, the data were subjected to visual analysis using CiteSpace, VOSviewer, the R package, and Bibliometric. This comprehensive approach aimed to elucidate the global state of research, as well as to identify prevailing trends and emerging hotspots within the field.

resultsA comprehensive analysis included 843 publications authored by 4451 researchers from 1096 institutions across 47 countries/regions, with relevant articles disseminated through 297 journals. China emerged as the leading contributor in terms of research output. Specifically, China Medical University and the researcher Chih-Hsin Tang were identified as the most influential institution and author, respectively. "Frontiers in Immunology" was recognized as the most prolific journal, whereas "Arthritis Research & Therapy" garnered the highest number of citations. Notably, Stanczyk's 2008 study published in "Arthritis & Rheumatism" received the highest citation count. Additionally, related research areas such as circular RNAs (circRNAs) and extracellular vesicles (EVs) have become new hotspots in the field.

conclusionsMiRNAs have garnered significant interest among researchers studying RA, as they show considerable potential for improving RA diagnosis and treatment. As research in this area advances, it is anticipated that scholars will allocate more resources to investigating circRNAs and EVs associated with miRNAs. This focus is expected to provide valuable insights for identifying novel therapeutic targets and drug delivery vectors for RA.

Indexed as

Arthritis, RheumatoidBibliometricsBiomedical ResearchMicroRNAsHumansMicroRNAsBibliometricsHotspotsMicroRNARheumatoid arthritisVisualization

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.