Evidence map›Paper›PMID 39604728›Full record

ArticleNature2024

Fungal symbiont transmitted by free-living mice promotes type 2 immunity.

Yun Liao, Iris H Gao, Takato Kusakabe, Woan-Yu Lin, Alexander Grier, Xiangyu Pan, Olga Morzhanaeva, Terrance P Shea, Hiroshi Yano, Danielle Karo-Atar and 9 more

Abstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Frontiers in immunology · 2026
    Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Commensal colonization ofMicrobiology spectrum · 2025
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Yun Liao *Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.ORCID 0000-0002-0829-8986
Iris H Gao *Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.ORCID 0000-0001-6514-3019
Takato KusakabeJoan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.
Woan-Yu LinJoan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.
Alexander GrierJoan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.
Xiangyu PanJoan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.
Olga MorzhanaevaJoan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.
Terrance P SheaInfectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Hiroshi YanoJoan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.ORCID 0000-0002-3098-2629
Danielle Karo-AtarDepartment of Microbiology and Immunology, Meakins-Christie Laboratories, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
Kaitlin A OlsenDepartment of Microbiology and Immunology, Meakins-Christie Laboratories, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
Ji Hoon OhImmunology Section, Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, DHHS, Bethesda, MD, USA.ORCID 0000-0002-0824-6131
Kurt J VandegriftDepartment of Biology, The Pennsylvania State University, University Park, PA, USA.
Irah L KingDepartment of Microbiology and Immunology, Meakins-Christie Laboratories, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
Christina A CuomoInfectious Disease and Microbiome Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0002-5778-960X
David ArtisJoan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.ORCID 0000-0002-1753-4100
Barbara RehermannImmunology Section, Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, DHHS, Bethesda, MD, USA.ORCID 0000-0001-6832-9951
Neil LipmanCenter for Comparative Medicine and Pathology, Memorial Sloan Kettering Cancer Center and Weill Cornell Medicine, New York, NY, USA.
Iliyan D IlievJoan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA. idi@ilievlab.org.ORCID 0000-0003-0884-9749

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Regulation of protective immunity following enteric viral infectionU01AI095608 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI ARTIS, DAVID, SONNENBERG, GREGORY F · 2011 to 2025
$11.0M
Microbiota-derived metabolites and the regulation of host immunity and inflammation (Diversity Supplement)R01AI172027 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI David Artis, Chun-Jun Guo · 2022 to 2026
$4.4M
Commensal fungal communities in the regulation of immunity and intestinal inflammation.R01DK113136 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI ILIYAN Dimitrov ILIEV · 2017 to 2026
$4.2M
Neuroimmune Regulation of Atopic DermatitisR01AR070116 · NIAMS · WASHINGTON UNIVERSITY · PI KIM, BRIAN · 2016 to 2021
$3.8M
Regulation and function of innate lymphoid cells in the gutR01AI095466 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI ARTIS, DAVID · 2011 to 2022
$3.7M
Neuropeptide-mediated regulation of antihelminth immunityR01AI151599 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI ARTIS, DAVID, SIRACUSA, MARK CHRISTOPHER · 2020 to 2024
$3.2M
Neuro-immune regulation of intestinal inflammationR01DK126871 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI ARTIS, DAVID · 2020 to 2024
$3.2M
Regulation and function of mucosal IgA immune responses to mycobiota in the gut.R01AI163007 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI ILIEV, ILIYAN DIMITROV · 2021 to 2025
$2.9M
Dietary Regulation of Intestinal Inflammation and RepairR01DK132244 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI ARTIS, DAVID, GUO, CHUN-JUN · 2022 to 2025
$2.7M
Mononuclear phagocyte networks in mycobiota regulation and antifungal immunity.R01DK121977 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI ILIEV, ILIYAN DIMITROV · 2020 to 2024
$2.7M
Investigation of gut microbiota metabolite-mediated transkingdom interactions with fungiR01AI178683 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI Chun-Jun Guo, ILIYAN Dimitrov ILIEV · 2024 to 2026
$2.5M
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA286920NIAID NIH HHS K99 AI180354NIAID NIH HHS R01 AI095466NIAID NIH HHS R01 AI134911NIAID NIH HHS R01 AI151599NIAID NIH HHS R01 AI163007NIAID NIH HHS R01 AI172027NIAID NIH HHS R01 AI178683NIAID NIH HHS U01 AI095608NIAMS NIH HHS R01 AR070116NIDDK NIH HHS R01 DK113136NIDDK NIH HHS R01 DK121977NIDDK NIH HHS R01 DK126871NIDDK NIH HHS R01 DK132244
6 · The paper itself

Abstract

The gut mycobiota is crucial for intestinal homeostasis and immune function

Indexed as

Gastrointestinal MicrobiomeImmunityInterleukin-33SaccharomycetalesSymbiosisAnimalsEosinophiliaFemaleGastrointestinal TractInterleukin-1 Receptor-Like 1 ProteinMaleMiceMice, Inbred BALB CMice, Inbred C57BLMice, KnockoutMycobiomeIl1rl1 protein, mouseIl33 protein, mouseInterleukin-1 Receptor-Like 1 ProteinInterleukin-33

Identifiers

PMID39604728
PMCPMC11733984

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.