Evidence map›Paper›PMID 39604694›Full record

ArticleCardiovascular and interventional radiology2025

Radiation Lobectomy in Adjunct to Double Vein Embolization to Reach Sufficient Future Liver Remnant in Patients with Colorectal Cancer Liver Metastases: A Case Series.

D Andel, K Ramdhani, A J A T Braat, R C G Bruijnen, G Bol, G Keane, M G E H Lam, O W Kranenburg, I H M Borel Rinkes, J Hagendoorn and 1 more

Abstract read
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In one paragraph

Article in Cardiovascular and interventional radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

D Andel *Department of Surgical Oncology, University Medical Center Utrecht, Cancer Center, 3508 GA, PO BOX 85500, Utrecht, The Netherlands. D.S.H.Andel-3@umcutrecht.nl.ORCID http://orcid.org/0000-0001-9858-868X
K Ramdhani *Department of Radiology and Nuclear Medicine, University Medical Center Utrecht, Cancer Center, Utrecht, The Netherlands.
A J A T BraatDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, Cancer Center, Utrecht, The Netherlands.
R C G BruijnenDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, Cancer Center, Utrecht, The Netherlands.
G BolDepartment of Medical Oncology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
G KeaneDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, Cancer Center, Utrecht, The Netherlands.
M G E H LamDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, Cancer Center, Utrecht, The Netherlands.
O W KranenburgDepartment of Surgical Oncology, University Medical Center Utrecht, Cancer Center, 3508 GA, PO BOX 85500, Utrecht, The Netherlands.
I H M Borel RinkesDepartment of Surgical Oncology, University Medical Center Utrecht, Cancer Center, 3508 GA, PO BOX 85500, Utrecht, The Netherlands.
J Hagendoorn *Department of Surgical Oncology, University Medical Center Utrecht, Cancer Center, 3508 GA, PO BOX 85500, Utrecht, The Netherlands.
M L J Smits *Department of Radiology and Nuclear Medicine, University Medical Center Utrecht, Cancer Center, Utrecht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe the outcome of radiation lobectomy (RL) after double vein embolization (portal vein embolization + hepatic vein embolization) for patients with insufficient future liver remnant growth. MATERIALS AND

methodsAll patients with insufficient FLR function (as determined by hepatobiliary scintigraphy (HIDA); < 2.7%/min/m

resultsFive patients with colorectal liver metastases were selected. After RL, 4/5 patients had sufficient FLR function. Overall, the median volumetric and functional increase of the FLR was 47.5% (range 5.8-102.8%) and 66.7% (range 0-233.3%), respectively, and within a median of 81 days. No severe toxicities were reported after adjunct RL. Two patients did not undergo surgery due to disease progression. Three patients underwent surgery. The postoperative stay was complicated by persistent bile leakage in one patient and respiratory insufficiency in another. There was no 90-day mortality.

conclusionRL was safely employed in adjunct to double vein embolization to induce a further increase in the FLR volume and function.

Indexed as

Colorectal NeoplasmsEmbolization, TherapeuticHepatectomyLiver NeoplasmsAgedFemaleHepatic VeinsHumansMaleMiddle AgedPortal VeinRetrospective StudiesTreatment Outcomecolorectal liver metastasesdouble vein embolizationhepatic vein embolizationportal vein embolizationradiation lobectomyradioembolization

Identifiers

PMID39604694

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.