Evidence map›Paper›PMID 39604509›Full record

ArticleScientific reports2024

Detection of enoxaparin and argatroban by use of the novel viscoelastic coagulometer ClotPro.

Johannes Gratz, Stefan Ulbing, Fabian Schäfer, Stefan Koch, Christoph Dibiasi, Marion Wiegele, Peter Quehenberger, Eva Schaden

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Johannes GratzDepartment of Anaesthesia, Intensive Care Medicine and Pain Medicine, Division of General Anaesthesia and Intensive Care Medicine, Medical University of Vienna, Währinger Gürtel 18-20, Wien, Vienna, 1090, Austria. johannes.gratz@meduniwien.ac.at.
Stefan UlbingDepartment of Anaesthesia, Intensive Care Medicine and Pain Medicine, Division of General Anaesthesia and Intensive Care Medicine, Medical University of Vienna, Währinger Gürtel 18-20, Wien, Vienna, 1090, Austria.
Fabian SchäferDepartment of Anaesthesia, Intensive Care Medicine and Pain Medicine, Division of General Anaesthesia and Intensive Care Medicine, Medical University of Vienna, Währinger Gürtel 18-20, Wien, Vienna, 1090, Austria.
Stefan KochDepartment of Anaesthesia, Intensive Care Medicine and Pain Medicine, Division of General Anaesthesia and Intensive Care Medicine, Medical University of Vienna, Währinger Gürtel 18-20, Wien, Vienna, 1090, Austria.
Christoph DibiasiDepartment of Anaesthesia, Intensive Care Medicine and Pain Medicine, Division of General Anaesthesia and Intensive Care Medicine, Medical University of Vienna, Währinger Gürtel 18-20, Wien, Vienna, 1090, Austria.
Marion WiegeleDepartment of Anaesthesia, Intensive Care Medicine and Pain Medicine, Division of General Anaesthesia and Intensive Care Medicine, Medical University of Vienna, Währinger Gürtel 18-20, Wien, Vienna, 1090, Austria.
Peter QuehenbergerDepartment of Laboratory Medicine, Medical University of Vienna, Währinger Gürtel 18-20, Wien, Vienna, 1090, Austria.
Eva SchadenDepartment of Anaesthesia, Intensive Care Medicine and Pain Medicine, Division of General Anaesthesia and Intensive Care Medicine, Medical University of Vienna, Währinger Gürtel 18-20, Wien, Vienna, 1090, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Owing to the simultaneous increase in the risk of thrombosis and bleeding in critically ill patients, point-of-care-available diagnostic tests to guide parenteral anticoagulation are warranted. We evaluated the detection of enoxaparin and argatroban, two commonly used parenteral anticoagulants, using the novel ClotPro viscoelastic coagulometer. For this experimental in vitro study at a tertiary care academic center, blood samples were drawn from twelve (six female, six male) healthy volunteers without intake of antithrombotic medication and no history of hemostatic disorders. Blood samples were spiked with enoxaparin (IU.ml

Indexed as

AnticoagulantsArginineBlood CoagulationEnoxaparinPipecolic AcidsSulfonamidesAdultBlood Coagulation TestsFemaleHumansMaleAnticoagulantsargatrobanArginineEnoxaparinPipecolic AcidsSulfonamidesAnticoagulantsCoagulation managementCritical carePoint-of-care testingViscoelastic haemostatic assays

Identifiers

PMID39604509
PMCPMC11603016

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.