Evidence map›Paper›PMID 39604502›Full record

ArticleScientific reports2024

Exploring the potential of 7,4'-di(diethylamino)flavylium as a novel photosensitizer for topical photodynamic therapy of skin cancer.

Patrícia Correia, Paula Araújo, Joana Marto, Helena Ribeiro, Nuno Mateus, Victor de Freitas, Joana Oliveira, Iva Fernandes

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Patrícia CorreiaREQUIMTE/LAQV, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Rua do Campo Alegre, s/n, 4169-007, Porto, Portugal.
Paula AraújoREQUIMTE/LAQV, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Rua do Campo Alegre, s/n, 4169-007, Porto, Portugal.
Joana MartoResearch Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Avenida Prof. Gama Pinto S/N, 1649-003, Lisboa, Portugal.
Helena RibeiroResearch Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Avenida Prof. Gama Pinto S/N, 1649-003, Lisboa, Portugal.
Nuno MateusREQUIMTE/LAQV, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Rua do Campo Alegre, s/n, 4169-007, Porto, Portugal.
Victor de FreitasREQUIMTE/LAQV, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Rua do Campo Alegre, s/n, 4169-007, Porto, Portugal.
Joana OliveiraREQUIMTE/LAQV, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Rua do Campo Alegre, s/n, 4169-007, Porto, Portugal. jsoliveira@fc.up.pt.
Iva FernandesREQUIMTE/LAQV, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Rua do Campo Alegre, s/n, 4169-007, Porto, Portugal. iva.fernandes@fc.up.pt.

Funding

Fundação para a Ciência e a Tecnologia 2022.00042.CEECIND/CP1724/CT0017Fundação para a Ciência e a Tecnologia CEECINST/00064/2021/CP2812/CT0004Fundação para a Ciência e a Tecnologia SFRH/BD/143309/2019Fundação para a Ciência e a Tecnologia SFRH/BD/150661/2020Ministério da Ciência, Tecnologia e Ensino Superior UIDB/50006/2020 DOI 10.54499/UIDB/50006/2020
6 · The paper itself

Abstract

Photodynamic therapy (PDT) is a minimally invasive therapeutic approach that has shown promising results in recent years, particularly in the dermatological clinical treatment of several pathologies, including neoplastic skin diseases. In light of the recent discovery of the photosensitizing properties of a water-soluble group of amino-based flavylium dyes, research efforts have led to the development of a novel synthetic dye with two diethylamino moieties in its structure, 7,4'-di(diethylamino)flavylium (7,4'diN(Et)

Indexed as

PhotochemotherapyPhotosensitizing AgentsSkin NeoplasmsCell Line, TumorCell SurvivalHumansHydrogelsHydrogelsPhotosensitizing Agents

Identifiers

PMID39604502
PMCPMC11603071

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.