ArticleBDJ open2024
Efficacy of topical anesthetics of lidocaine, benzocaine, and EMLA in reducing pain during inferior alveolar nerve block in schoolchildren: a randomized controlled trial.
Article in BDJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Orodispersible lidocaine film in palatine nerve block: a randomized, controlled and blind clinical trial.Odontology · 2026Article
- Procedural Pain, Hall Technique Crowns and Separators: A Randomized Controlled Clinical Pilot Feasibility Study.International journal of clinical pediatric dentistry · 2026Article
- Evaluating the most effective combination of needle gauge with TENS, EMLA or topical spray for minimal pain during pediatric local anaesthesia: A randomized clinical trial.Bioinformation · 2026Article
- Compound lidocaine cream with warm compress for pain relief in ultrasound-guided peripherally inserted central catheter placement for cancer patients.World journal of clinical oncology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study aimed to evaluate the efficacy of 5% EMLA cream and 8% lidocaine gel in reducing pain during inferior alveolar nerve block (IANB) compared with 20% Benzocaine in children aged 6-10 years. MATERIALS AND
methodsThis was a triple-blinded, randomized, parallel-group, active-controlled trial with three arms. 45 children were randomly assigned into 3 groups. Group 1: control group, 20% benzocaine gel (n = 15). Group 2: 8% lidocaine gel (n = 15). Group 3: 5% EMLA cream (n = 15). Each topical anesthetic was applied in an amount of 0.3 mL using a cotton swab for 2 min, followed by IANB administration. The following primary outcome measures were considered: pulse rate, the face, legs, activity, cry, consolability (FLACC) behavioral pain assessment scale, and the Wong-Baker FACES pain rating scale.
resultsThe mean score of the FLACC behavioral pain assessment scale in group 2 (2.20 ± 1.86) was slightly higher, but this result was not statistically significant p = (0.806). Regarding the Wong-Baker FACES pain rating scale scores, no statistically significant difference was noted between the study groups p = (0.593). After IANB administration, the mean pulse rate was higher in group 3 (102.40 ± 14.28). However, this difference was not statistically significant p = (0.351). In addition, the mean change of the pulse rate from the baseline to this time point was not statistically significant p = (0.638), indicating a smaller physiologic response to the painful stimulus.
conclusion8% lidocaine gel was not superior to 20% benzocaine nor 5% EMLA in reducing pain during IANB administration.
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Registered trials
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