Evidence map›Paper›PMID 39604356›Full record

ArticleNature communications2024

Structural effects of high laser power densities on an early bacteriorhodopsin photocycle intermediate.

Quentin Bertrand, Przemyslaw Nogly, Eriko Nango, Demet Kekilli, Georgii Khusainov, Antonia Furrer, Daniel James, Florian Dworkowski, Petr Skopintsev, Sandra Mous and 22 more

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. TheJournal of applied crystallography · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Quentin BertrandDivision of Biology and Chemistry, Paul Scherrer Institut, Villigen, Switzerland.ORCID 0000-0003-3476-1775
Przemyslaw NoglyDivision of Biology and Chemistry, Paul Scherrer Institut, Villigen, Switzerland.ORCID 0000-0002-8040-7753
Eriko NangoRIKEN Spring-8 Center, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo, Japan.ORCID 0000-0001-9851-7355
Demet KekilliDivision of Biology and Chemistry, Paul Scherrer Institut, Villigen, Switzerland.
Georgii KhusainovDivision of Biology and Chemistry, Paul Scherrer Institut, Villigen, Switzerland.
Antonia FurrerDivision of Biology and Chemistry, Paul Scherrer Institut, Villigen, Switzerland.ORCID 0000-0001-9894-6985
Daniel JamesDivision of Biology and Chemistry, Paul Scherrer Institut, Villigen, Switzerland.
Florian DworkowskiPhoton Science Division, Paul Scherrer Institut, Villigen, Switzerland.ORCID 0000-0001-5004-8684
Petr SkopintsevDivision of Biology and Chemistry, Paul Scherrer Institut, Villigen, Switzerland.
Sandra MousDivision of Biology and Chemistry, Paul Scherrer Institut, Villigen, Switzerland.
Isabelle MartielPhoton Science Division, Paul Scherrer Institut, Villigen, Switzerland.
Per BörjessonDepartment of Chemistry and Molecular Biology, University of Gothenburg, Box 462, Gothenburg, Sweden.ORCID 0000-0002-7193-640X
Giorgia OrtolaniDepartment of Chemistry and Molecular Biology, University of Gothenburg, Box 462, Gothenburg, Sweden.ORCID 0000-0001-6373-9919
Chia-Ying HuangPhoton Science Division, Paul Scherrer Institut, Villigen, Switzerland.ORCID 0000-0002-7676-0239
Michal KepaDivision of Biology and Chemistry, Paul Scherrer Institut, Villigen, Switzerland.ORCID 0000-0002-4045-3990
Dmitry OzerovPhoton Science Division, Paul Scherrer Institut, Villigen, Switzerland.ORCID 0000-0002-3274-1124
Steffen BrünleDivision of Biology and Chemistry, Paul Scherrer Institut, Villigen, Switzerland.
Valerie PanneelsDivision of Biology and Chemistry, Paul Scherrer Institut, Villigen, Switzerland.ORCID 0000-0001-8899-3366
Tomoyuki TanakaRIKEN Spring-8 Center, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo, Japan.
Rie TanakaRIKEN Spring-8 Center, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo, Japan.
Kensuke TonoJapan Synchrotron Radiation Research Institute, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo, Japan.ORCID 0000-0003-1218-3759
Shigeki OwadaRIKEN Spring-8 Center, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo, Japan.
Philip J M JohnsonPhoton Science Division, Paul Scherrer Institut, Villigen, Switzerland.ORCID 0000-0002-7251-4815
Karol NassPhoton Science Division, Paul Scherrer Institut, Villigen, Switzerland.
Gregor KnoppPhoton Science Division, Paul Scherrer Institut, Villigen, Switzerland.ORCID 0000-0002-0786-3402
Claudio CirelliPhoton Science Division, Paul Scherrer Institut, Villigen, Switzerland.ORCID 0000-0003-4576-3805
Christopher MilnePhoton Science Division, Paul Scherrer Institut, Villigen, Switzerland.ORCID 0000-0003-4714-9139
Gebhard SchertlerDivision of Biology and Chemistry, Paul Scherrer Institut, Villigen, Switzerland.ORCID 0000-0002-5846-6810
So IwataDepartment of Cell Biology, Graduate School of Medicine, Kyoto University, Yoshidakonoe-cho, Sakyo-ku, Kyoto, Japan.ORCID 0000-0003-1735-2937
Richard NeutzeDepartment of Chemistry and Molecular Biology, University of Gothenburg, Box 462, Gothenburg, Sweden.ORCID 0000-0003-0986-6153
Tobias WeinertDivision of Biology and Chemistry, Paul Scherrer Institut, Villigen, Switzerland. tobias.weinert@psi.ch.ORCID 0000-0002-0339-3722
Jörg StandfussDivision of Biology and Chemistry, Paul Scherrer Institut, Villigen, Switzerland. joerg.standfuss@psi.ch.ORCID 0000-0001-8825-386X

Funding

High-Repetition Rate X-ray Detector for the Coherent X-ray Imaging Instrument at LCLSS10OD025079 · OD · STANFORD UNIVERSITY · PI BOUTET, SEBASTIEN · 2018 to 2018
$524k
NIH HHS S10 OD025079
6 · The paper itself

Abstract

Time-resolved serial crystallography at X-ray Free Electron Lasers offers the opportunity to observe ultrafast photochemical reactions at the atomic level. The technique has yielded exciting molecular insights into various biological processes including light sensing and photochemical energy conversion. However, to achieve sufficient levels of activation within an optically dense crystal, high laser power densities are often used, which has led to an ongoing debate to which extent photodamage may compromise interpretation of the results. Here we compare time-resolved serial crystallographic data of the bacteriorhodopsin K-intermediate collected at laser power densities ranging from 0.04 to 2493 GW/cm

Indexed as

BacteriorhodopsinsLasersCrystallography, X-RayLightModels, MolecularPhotochemical ProcessesPhotonsProtein ConformationBacteriorhodopsins

Identifiers

PMID39604356
PMCPMC11603225

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.