ArticleEuropean burn journal2022
The Use of Intact Fish Skin as a Novel Treatment Method for Deep Dermal Burns Following Enzymatic Debridement: A Retrospective Case-Control Study.
Article in European burn journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The use of xenografts with fish skin for the treatment of burns: a systematic review and meta-analysis.Acta cirurgica brasileira · 2026Pooled it
- Bromelain-based enzymatic burn debridement: A systematic review of clinical studies on patient safety, efficacy and long-term outcomes.International wound journal · 2023Pooled it
- The Use of Acellular Fish Skin Grafts in Burn Wound Management-A Systematic Review.Medicina (Kaunas, Lithuania) · 2022Pooled it
- Two-stage reconstruction using basic fibroblast growth factor-impregnated artificial dermis and acellular fish skin graft in a dog with distal extremity soft tissue sarcoma.The Journal of veterinary medical science · 2026Article
- The Use of Kerecis Omega3 Wound Fish Skin Graft for the Treatment of Deep Burn Wounds.Plastic and reconstructive surgery. Global open · 2026Article
- Investigating the Role of Fish Skin Grafts in Treating Complex Posterior Spinal Wounds.Plastic and reconstructive surgery. Global open · 2026Article
- From the Ocean to the Operating Room: The Role of Fish Skin Grafts in Burn Management-A Systematic Review.Journal of clinical medicine · 2025Review
- Serial irrigation and debridement with the use of Kerecis in the treatment of necrotizing fasciitis: A case report.Trauma case reports · 2025Article
- Individualized surgical treatment using decellularized fish skin transplantation after enzymatic debridement: A two years retrospective analysis.JPRAS open · 2025Article
- Acellular fish skin grafts in diabetic foot ulcer care: Advances and clinical insights.World journal of diabetes · 2025Article
- COMPARATIVE STUDY OF STRIPED CATFISHAnnals of burns and fire disasters · 2024Article
- The Use of Fish Skin Grafts in Children as a New Treatment of Deep Dermal Burns-Case Series with Follow-Up after 2 Years and Measurement of Elasticity as an Objective Scar Evaluation.Journal of clinical medicine · 2024Article
- Assessment of Tilapia Skin Collagen for Biomedical Research Applications in Comparison with Mammalian Collagen.Molecules (Basel, Switzerland) · 2024Article
- An Overview of Recent Developments in the Management of Burn Injuries.International journal of molecular sciences · 2023Review
- The Use of Intact Fish Skin Grafts in the Treatment of Necrotizing Fasciitis of the Leg: Early Clinical Experience and Literature Review on Indications for Intact Fish Skin Grafts.Journal of clinical medicine · 2023Review
- Acellular fish skin for wound healing.International wound journal · 2023Review
- Fish Skin Graft: Narrative Review and First Application for Abdominal Wall Dehiscence in Children.Plastic and reconstructive surgery. Global open · 2023Article
- Fish Skin Grafts Versus Alternative Wound Dressings in Wound Care: A Systematic Review of the Literature.Cureus · 2023Review
- Review
- Gender Affirming Revision Vaginoplasty Utilizing Decellularized Fish Skin Xenograft: Surgical Technique and Outcomes.International braz j urol : official journal of the Brazilian Society of UrologyArticle
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe optimal therapy for deep burn wounds is based on the early debridement of necrotic tissue followed by wound coverage to avoid a systemic inflammatory response and optimize scar-free healing. The outcomes are affected by available resources and underlying patient factors, which represent challenges in burn care and suboptimal outcomes. In this study, we aimed to determine optimal burn-wound management using enzymatic debridement (NexoBrid™, MediWound Germany GmbH, Rüsselsheim, Germany) and intact fish skin (Kerecis
methodsIn this retrospective case series, 12 patients with superficial or deep dermal burn wounds were treated with enzymatic debridement followed by fish skin, Suprathel
resultsWounds treated with fish skin demonstrated accelerated wound healing, a significantly higher water-storage capacity, and better pain relief. Furthermore, improved functional and cosmetic outcomes, such as elasticity, skin thickness, and pigmentation, were demonstrated. The pain and itch expressed as POSAS scores (Patient and Observer Scar Assessment Scale) for fish skin decreased compared to those for wounds managed with an STSG or Suprathel. Importantly, fish skin-treated wounds had significantly improved sebum production and skin elasticity than those treated with Suprathel but showed no significant superiority compared to STSG-treated wounds.
conclusionsEnzymatic debridement in combination with intact fish skin grafts resulted in the faster healing of burn wounds and better functional and aesthetic outcomes than split-thickness skin grafts and Suprathel treatment.
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