Evidence map›Paper›PMID 39603790›Full record

ArticleHeart (British Cardiac Society)2025

Surgical and transcatheter aortic valve interventions for aortic stenosis in England: sociodemographic variations in treatment trends and outcome over 20 years.

Anvesha Singh, Fionna Chalmers, Saadia Aslam, Thomas Bolton, Anna Stevenson, Iain Squire, Kamlesh Khunti, Gerry P McCann, Claire Lawson

Abstract read
In one paragraph

Article in Heart (British Cardiac Society), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Anvesha SinghDepartment of Cardiovascular Sciences, University of Leicester and the NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK as707@le.ac.uk.ORCID 0000-0003-1112-3973
Fionna ChalmersBritish Heart Foundation Data Science Centre, Health Data Research UK, London, UK.
Saadia AslamDepartment of Cardiovascular Sciences, University of Leicester and the NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.ORCID 0000-0002-8370-186X
Thomas BoltonBritish Heart Foundation Data Science Centre, Health Data Research UK, London, UK.
Anna StevensonBritish Heart Foundation Data Science Centre, Health Data Research UK, London, UK.
Iain SquireDepartment of Cardiovascular Sciences, University of Leicester and the NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.ORCID 0000-0002-6282-4318
Kamlesh KhuntiLeicester Diabetes Centre, Leicester General Hospital, University of Leicester, Leicester, UK.
Gerry P McCannDepartment of Cardiovascular Sciences, University of Leicester and the NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.ORCID 0000-0002-5542-8448
Claire LawsonDepartment of Cardiovascular Sciences, University of Leicester and the NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.ORCID 0000-0003-0127-5236

Funding

British Heart Foundation SP/19/3/34678
6 · The paper itself

Abstract

backgroundHealth inequalities in cardiovascular care have been identified in the UK. The sociodemographic characteristics of patients undergoing intervention for aortic stenosis (AS) in England, and the impact of COVID-19, is unknown.

methodsNational linked data sets identified all surgical aortic valve replacement (SAVR) and transcatheter aortic valve implantation (TAVI) for AS, and post-intervention cardiovascular mortality, between 2000 and 2023.

resultsOf 179 645 procedures, there were 139 990 SAVR (mean age 71±10.8 years, 64% male, 96.0% white) and 39 655 TAVI (mean age 81±7.7 years, 57% male, 95.7% white). Rates of SAVR declined during COVID-19 for all groups, but TAVI rates increased steadily. Women were older; ethnic minority groups and those from most deprived areas were younger, with greater comorbidities. Women and more deprived groups had lower rates of SAVR (age-standardised rates per 100 000 in 2020-2023: 17.07

conclusionsThere are differences in intervention rates for AS in England, with lower rates in female patients and to a lesser extent, those from the most deprived areas and ethnic minority groups. These variations have widened over time. Post-intervention cardiovascular mortality is lower in women and with decreasing deprivation. Public health measures and research are needed to identify the true prevalence of AS in different populations, and the reasons for potential inequalities.

Indexed as

Aortic Valve StenosisCOVID-19Healthcare DisparitiesHeart Valve Prosthesis ImplantationTranscatheter Aortic Valve ReplacementAgedAged, 80 and overEnglandFemaleHumansMaleSARS-CoV-2Treatment OutcomeAortic Valve StenosisCohort StudiesCOVID-19Heart Valve Prosthesis ImplantationTranscatheter Aortic Valve Replacement

Identifiers

PMID39603790
PMCPMC11874321

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.