Evidence map›Paper›PMID 39603629›Full record

ArticleInternal medicine (Tokyo, Japan)2025

An Autopsied Case of Erdheim-Chester Disease with Severe Cardiovascular Involvement.

Atsushi Matsunashi, Wang Zhipeng, Akihiko Sugimoto, Masakazu Fujimoto, Akihiko Yoshizawa, Ryo Sakamoto, Michihiro Uyama, Kohei Ikezoe, Kiminobu Tanizawa, Tomohiro Handa and 1 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Atsushi MatsunashiDepartment of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Japan.
Wang ZhipengDepartment of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Japan.
Akihiko SugimotoDepartment of Diagnostic Pathology, Graduate School of Medicine, Kyoto University, Japan.
Masakazu FujimotoDepartment of Diagnostic Pathology, Graduate School of Medicine, Kyoto University, Japan.
Akihiko YoshizawaDepartment of Diagnostic Pathology, Nara Medical University, Japan.
Ryo SakamotoDepartment of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, Japan.
Michihiro UyamaDepartment of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Japan.
Kohei IkezoeDepartment of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Japan.
Kiminobu TanizawaDepartment of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Japan.
Tomohiro HandaDepartment of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Japan.
Toyohiro HiraiDepartment of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Erdheim-Chester disease (ECD) is a rare type of non-Langerhans cell histiocytosis, characterized by the infiltration of disease-specific foamy histiocytes, polymorphic granulomas, and fibrosis. Although cardiovascular involvement is observed radiologically in approximately half of ECD patients, only a few reports have described its pathological features. We herein report the autopsy of an ECD patient with pulmonary, cardiovascular, and retroperitoneal involvement that may have caused his death. Autopsy revealed the pathological association of coronary and renal arterial stenosis with the BRAF

Indexed as

Erdheim-Chester DiseaseAutopsyFatal OutcomeHumansMaleMiddle AgedProto-Oncogene Proteins B-rafBRAF protein, humanProto-Oncogene Proteins B-rafautopsyBRAFV600E mutationcardiovascular lesionErdheim-Chester diseasepulmonary lesion

Identifiers

PMID39603629
PMCPMC12241793

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.