Evidence map›Paper›PMID 39603624›Full record

ReviewInternal medicine (Tokyo, Japan)2025

Surgical Treatment of Hepatocellular Carcinoma Arising from Fontan-associated Liver Disease: A Report of Three Cases.

Koji Rinka, Kiyohide Kioka, Yuga Amano, Takashi Nakai, Yasuko Kawasaki, Yuki Kawasaki, Hisashi Sugiyama, Takeshi Inoue, Norifumi Kawada

Abstract readCase ReportsReview
In one paragraph

Review in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Koji RinkaDepartment of Gastroenterology Osaka City General Hospital, Japan.
Kiyohide KiokaDepartment of Gastroenterology Osaka City General Hospital, Japan.
Yuga AmanoDepartment of Gastroenterology Osaka City General Hospital, Japan.
Takashi NakaiDepartment of Gastroenterology Osaka City General Hospital, Japan.
Yasuko KawasakiDepartment of Gastroenterology Osaka City General Hospital, Japan.
Yuki KawasakiDepartment of Pediatric Cardiology and Electrophysiology, Osaka City General Hospital, Japan.
Hisashi SugiyamaDepartment of Pediatric Cardiology and Electrophysiology, Osaka City General Hospital, Japan.
Takeshi InoueDepartment of Pathology, Osaka City General Hospital, Japan.
Norifumi KawadaDepartment of Hepatology, Osaka Metropolitan University Graduate School of Medicine, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report three patients with Fontan-associated liver disease (FALD) who developed hepatocellular carcinoma (HCC). All three patients had very high serum alpha-fetoprotein (AFP) concentrations, and their HCCs were located in the peripheral areas of the liver. To identify the characteristics of FALD-HCC, we reviewed previously published case reports that included descriptions of imaging. This review revealed that FALD-HCC is generally located in the peripheral areas of the liver and AFP concentrations are usually high. Thus, it is important that follow-up of patients with FALD include repeated AFP concentrations and abdominal imaging.

Indexed as

Carcinoma, HepatocellularFontan ProcedureLiver DiseasesLiver NeoplasmsAdultalpha-FetoproteinsFemaleHumansMaleMiddle Agedalpha-FetoproteinsFontan-associated liver diseaseFontan procedurehepatocellular carcinoma

Identifiers

PMID39603624
PMCPMC12241794

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.