Evidence map›Paper›PMID 39603330›Full record

ArticleAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2025

Establishing Research Priorities in Geriatric Nephrology: A Delphi Study of Clinicians and Researchers.

Catherine R Butler, Akanksha Nalatwad, Katharine L Cheung, Mary F Hannan, Melissa D Hladek, Emily A Johnston, Laura Kimberly, Christine K Liu, Devika Nair, Semra Ozdemir and 10 more

Abstract read
In one paragraph

Article in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Catherine R ButlerDivision of Nephrology, Department of Medicine, Kidney Research Institute, University of Washington, Seattle, Washington; Veterans Affairs Health Services Research and Development Center of Innovation for Veteran-Centered and Value-Driven Care, Seattle, Washington.
Akanksha NalatwadDepartment of Surgery, New York University Grossman School of Medicine and Langone Health, New York, New York.
Katharine L CheungDivision of Nephrology, Department of Medicine, The University of Vermont Larner College of Medicine, Burlington, Vermont.
Mary F HannanDepartment of Biobehavioral Nursing Science, College of Nursing, University of Illinois Chicago, Chicago, Illinois.
Melissa D HladekSchool of Nursing, Johns Hopkins University, Baltimore, Maryland.
Emily A JohnstonDivision of Geriatrics and Palliative Care, Department of Medicine, New York University Grossman School of Medicine and Langone Health, New York, New York.
Laura KimberlyHansjörg Wyss Department of Plastic Surgery, Department of Population Health, Division of Medical Ethics, New York University Grossman School of Medicine and Langone Health, New York, New York.
Christine K LiuGeriatric Research and Education Clinical Center, Veteran Affairs Palo Alto Health Care System, Palo Alto, California; Section of Geriatric Medicine, Division of Primary Care and Population Health, Stanford University School of Medicine, Stanford, California.
Devika NairDivision of Nephrology and Hypertension, Vanderbilt University Medical Center, Nashville, Tennessee; Tennessee Valley Veterans Affairs Health System, Nashville, Tennessee.
Semra OzdemirDepartment of Population Health Sciences, Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina.
Fahad SaeedDivisions of Nephrology and Palliative Care, Departments of Medicine and Public Health, University of Rochester Medical Center, Rochester, New York.
Jennifer S SchererDivision of Geriatrics and Palliative Care, Division of Nephrology, Department of Internal Medicine, New York University Grossman School of Medicine and Langone Health, New York, New York.
Dorry L SegevDepartment of Surgery, New York University Grossman School of Medicine and Langone Health, New York, New York; Division of Nephrology and Hypertension, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Population Health, New York University Grossman School of Medicine and Langone Health, New York, New York.
Anoop SheshadriDivision of Nephrology, Department of Medicine, University of California San Francisco, San Francisco, California; Nephrology Section, San Francisco Veterans Affairs Medical Center, San Francisco, California.
Karthik K TennankoreDivision of Nephrology, Department of Medicine, Dalhousie University, Halifax, NS, Canada.
Tiffany R WashingtonCollege of Social Work, University of Tennessee, Knoxville, Tennessee.
Dawn WolfgramDepartment of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin; Medicine Division, Milwaukee Veterans Affairs Medical Center, Milwaukee, Wisconsin.
Nidhi GhildayalDepartment of Surgery, New York University Grossman School of Medicine and Langone Health, New York, New York.
Rasheeda HallDivision of Nephrology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina; Renal Section, Durham Veterans Affairs Healthcare System, Durham, North Carolina.
Mara McAdams-DeMarcoDepartment of Surgery, New York University Grossman School of Medicine and Langone Health, New York, New York; Department of Population Health, New York University Grossman School of Medicine and Langone Health, New York, New York. Electronic address: mara.mcadamsdemarco@nyulangone.org.

Funding

Understanding Factors Influencing COVID-19 Testing and Vaccination in Immigrant Low-income and Homeless Populations and Testing Targeted InterventionsU54GM115516 · NIGMS · MAINEHEALTH · PI CLIFFORD JAMES ROSEN, Gary S. Stein · 2017 to 2026
$51.6M
Technological Assessment and Solutions Core - RC4P30AG021334 · NIA · JOHNS HOPKINS UNIVERSITY · PI Jeremy D Walston · 2003 to 2026
$33.2M
VARC CoreP30AG044281 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Alexander Keliimoeanu Smith · 2013 to 2026
$19.9M
Institutional Career Development Core SupplementKL2TR001870 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KANAYA, ALKA M., SARKAR, URMIMALA · 2016 to 2025
$19.7M
Structural Racism, Resilience, and Premature Cognitive Aging in End-Stage Renal Disease - Revision - 5R01AG077888 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Mara A. McAdams DeMarco · 2022 to 2026
$4.4M
Hemodialysis-based interventions to preserve cognitive functionR01DK114074 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MCADAMS DEMARCO, MARA A. · 2018 to 2022
$3.9M
Developing personalized immunosuppression for older kidney transplant recipientsR01DK120518 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MCADAMS DEMARCO, MARA A. · 2019 to 2022
$2.7M
Outcomes of a Palliative Care Intervention to Improve Kidney Therapy-Decision Making for Older People with Advanced CKDR01AG082891 · NIA · UNIVERSITY OF ROCHESTER · PI Fahad Saeed · 2024 to 2026
$2.0M
Kidney Disease Aging Research Collaborative (KDARC) Research Infrastructure to Advance the Science of Geriatric NephrologyR61AG086824 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI HALL, RASHEEDA K, MCADAMS DEMARCO, MARA A. · 2024 to 2025
$1.7M
Deprescribing for Older Dialysis PatientsK76AG059930 · NIA · DUKE UNIVERSITY · PI HALL, RASHEEDA K · 2018 to 2022
$1.2M
Supportive Care in Kidney Disease: Scope of Practice and Pilot Study of ImplementationK23DK125840 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SCHERER, JENNIFER S · 2020 to 2024
$962k
Patient Oriented Research in Solid Organ TransplantationK24AI144954 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SEGEV, DORRY L. · 2020 to 2024
$956k
CSRD VA IK2 CX002595NCATS NIH HHS KL2 TR001870NIAID NIH HHS K24 AI144954NIA NIH HHS K02 AG076883NIA NIH HHS K76 AG059930NIA NIH HHS L30 AG096718NIA NIH HHS P30 AG021334NIA NIH HHS P30 AG044281NIA NIH HHS R01 AG077888NIA NIH HHS R01 AG082891NIA NIH HHS R03 AG067981NIA NIH HHS R61 AG086824NIDDK NIH HHS K23 DK121939NIDDK NIH HHS K23 DK125840NIDDK NIH HHS K23 DK129777NIDDK NIH HHS K23 DK133677NIDDK NIH HHS R01 DK114074NIDDK NIH HHS R01 DK120518NIDDK NIH HHS R03 DK132441NIGMS NIH HHS U54 GM115516
6 · The paper itself

Abstract

RATIONALE &

objectiveDespite substantial growth of the population of older adults with kidney disease, there remains a lack of evidence to guide clinical care for this group. The Kidney Disease and Aging Research Collaborative conducted a Delphi study to build consensus on research priorities for clinical geriatric nephrology. STUDY

designAsynchronous modified Delphi study. SETTING &

participantsClinicians and researchers in the United States and Canada with clinical experience and/or research expertise in geriatric nephrology. OUTCOME: Research priorities in geriatric nephrology. ANALYTICAL APPROACH: In the first Delphi round, participants submitted free-text descriptions of research priorities considered important for improving the clinical care of older adults with kidney disease. Delphi moderators used inductive content analysis to group concepts into categories. In the second and third rounds, participants iteratively reviewed topics, selected their top 5 priorities, and offered comments used to revise categories.

resultsAmong 121 who were invited, 57 participants (47%) completed the first Delphi round and 48 (84% of enrolled participants) completed all rounds. After 3 rounds, the 5 priorities with the highest proportion of agreement were (1) communication and decision-making about treatment options for older adults with kidney failure (69% agreement), (2) quality of life, symptom management, and palliative care (67%), (3) frailty and physical function (54%), (4) tailoring therapies for kidney disease to specific needs of older adults (42%), and (5) caregiver and social support (35%). Health equity and person-centricity were identified as cross-cutting features that informed all topics. LIMITATIONS: Relatively low response rate and limited participation by private practitioners and older clinicians and researchers.

conclusionsExperts in geriatric nephrology identified clinical research priorities with the greatest potential to improve care for older adults with kidney disease. These findings provide a road map for the geriatric nephrology community to harmonize and maximize the impact of research efforts.

Indexed as

Biomedical ResearchGeriatricsNephrologyResearch PersonnelAgedCanadaDelphi TechniqueFemaleHumansMaleMiddle AgedUnited StatesDelphi studygeriatric nephrology

Identifiers

PMID39603330
PMCPMC11846693

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.