Evidence map›Paper›PMID 39602801›Full record

ArticleJournal of medical Internet research2024

Preliminary Screening for Hereditary Breast and Ovarian Cancer Using an AI Chatbot as a Genetic Counselor: Clinical Study.

Ann Sato, Eri Haneda, Yukihiko Hiroshima, Hiroto Narimatsu

Registry-linked trialAbstract read
In one paragraph

Article in Journal of medical Internet research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06943911 (Empowering Breast Cancer Clients Through AI Chatbots), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06943911 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Empowering Breast Cancer Clients Through AI Chatbots: Transforming Knowledge and Attitudes for Enhanced Nursing Care

TypeinterventionalSponsorMostafa ShabanRan2025 to 2025Enrolled122ConditionsBreast Cancer Early Stage Breast Cancer (Stage 1-3)ArmsAI Chatbot for Breast Cancer Patient Education and Empowerment
3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Large-Scale Population Screening forBreast care (Basel, Switzerland) · 2025
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ann SatoDepartment of Genetic Medicine, Kanagawa Cancer Center, Yokohama, Kanagawa, Japan.ORCID 0000-0002-5572-3893
Eri HanedaDepartment of Genetic Medicine, Kanagawa Cancer Center, Yokohama, Kanagawa, Japan.ORCID 0000-0003-2660-9028
Yukihiko HiroshimaDepartment of Cancer Genome Medicine, Kanagawa Cancer Center, Yokohama, Kanagawa, Japan.ORCID 0009-0005-7384-3513
Hiroto NarimatsuDepartment of Genetic Medicine, Kanagawa Cancer Center, Yokohama, Kanagawa, Japan.ORCID 0000-0002-0383-4911

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHereditary breast and ovarian cancer (HBOC) is a major type of hereditary cancer. Establishing effective screening to identify high-risk individuals for HBOC remains a challenge. We developed a prototype of a chatbot system that uses artificial intelligence (AI) for preliminary HBOC screening to determine whether individuals meet the National Comprehensive Cancer Network BRCA1/2 testing criteria.

objectiveThis study's objective was to validate the feasibility of this chatbot in a clinical setting by using it on a patient population that visited a hospital.

methodsWe validated the medical accuracy of the chatbot system by performing a test on patients who consecutively visited the Kanagawa Cancer Center. The participants completed a preoperation questionnaire to understand their background, including information technology literacy. After the operation, qualitative interviews were conducted to collect data on the usability and acceptability of the system and examine points needing improvement.

resultsA total of 11 participants were enrolled between October and December 2020. All of the participants were women, and among them, 10 (91%) had cancer. According to the questionnaire, 6 (54%) participants had never heard of a chatbot, while 7 (64%) had never used one. All participants were able to complete the chatbot operation, and the average time required for the operation was 18.0 (SD 5.44) minutes. The determinations by the chatbot of whether the participants met the BRCA1/2 testing criteria based on their medical and family history were consistent with those by certified genetic counselors (CGCs). We compared the medical histories obtained from the participants by the CGCs with those by the chatbot. Of the 11 participants, 3 (27%) entered information different from that obtained by the CGCs. These discrepancies were caused by the participant's omissions or communication errors with the chatbot. Regarding the family histories, the chatbot provided new information for 3 (27%) of the 11 participants and complemented information for the family members of 5 (45%) participants not interviewed by the CGCs. The chatbot could not obtain some information on the family history of 6 (54%) participants due to several reasons, such as being outside of the scope of the chatbot's interview questions, the participant's omissions, and communication errors with the chatbot. Interview data were classified into the following: (1) features, (2) appearance, (3) usability and preferences, (4) concerns, (5) benefits, and (6) implementation. Favorable comments on implementation feasibility and comments on improvements were also obtained.

conclusionsThis study demonstrated that the preliminary screening system for HBOC using an AI chatbot was feasible for real patients.

Indexed as

Artificial IntelligenceGenetic CounselingAdultBreast NeoplasmsFemaleGenetic TestingHereditary Breast and Ovarian Cancer SyndromeHumansMiddle AgedOvarian NeoplasmsSurveys and QuestionnairesacceptabilityAIartificial intelligencebreast cancercancerchatbotconversational agentcounsellingfamilial cancerfamily historyfeasibilitygenetichereditary cancerIBM Watsonimplementationmedical historyoncologyovarian cancerscreeningsocial networkusability

Identifiers

PMID39602801
PMCPMC11635313

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.