Evidence map›Paper›PMID 39602788›Full record

ArticleJournal of medical Internet research2024

Predicting Early Dropout in a Digital Tobacco Cessation Intervention: Replication and Extension Study.

Linda Q Yu, Michael S Amato, George D Papandonatos, Sarah Cha, Amanda L Graham

Abstract read
In one paragraph

Article in Journal of medical Internet research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Linda Q YuInnovations Center, Truth Initiative, Washington, DC, United States.ORCID 0000-0002-4658-9100
Michael S AmatoInnovations Center, Truth Initiative, Washington, DC, United States.ORCID 0000-0002-9769-957X
George D PapandonatosCenter for Statistical Sciences, School of Public Health, Brown University, Providence, RI, United States.ORCID 0000-0001-6770-932X
Sarah ChaInnovations Center, Truth Initiative, Washington, DC, United States.ORCID 0000-0003-3505-3164
Amanda L GrahamInnovations Center, Truth Initiative, Washington, DC, United States.ORCID 0000-0003-3036-9653

Funding

Trial of a harm reduction strategy for people with HIV who smoke cigarettesR01CA275521 · NCI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI Jonathan Shuter · 2023 to 2026
$3.0M
ACT on Vaping: Digital Therapeutic for Young Adult Vaping CessationUG3DA057032 · NIDA · FRED HUTCHINSON CANCER CENTER · PI HEFFNER, JAIMEE · 2022 to 2023
$1.5M
Adapting a Digital Intervention to Improve Smoking Cessation in Persons with Serious Mental IllnessR34MH120142 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI BENNETT, MELANIE E., DICKERSON, FAITH · 2020 to 2020
$666k
Addressing the Vaping Epidemic in Adolescents and Young Adults: Advancing our Understanding of Cessation Treatment and EngagementK08DA058058 · NIDA · UNIVERSITY OF WISCONSIN-MADISON · PI Brian S Williams · 2024 to 2026
$580k
NCI NIH HHS R01 CA275521NIDA NIH HHS K08 DA058058NIDA NIH HHS UG3 DA057032NIMH NIH HHS R34 MH120142
6 · The paper itself

Abstract

backgroundDetecting early dropout from digital interventions is crucial for developing strategies to enhance user retention and improve health-related behavioral outcomes. Bricker and colleagues proposed a single metric that accurately predicted early dropout from 4 digital tobacco cessation interventions based on log-in data in the initial week after registration. Generalization of this method to additional interventions and modalities would strengthen confidence in the approach and facilitate additional research drawing on it to increase user retention.

objectiveThis study had two research questions (RQ): RQ1-can the study by Bricker and colleagues be replicated using data from a large-scale observational, multimodal intervention to predict early dropout? and RQ2-can first-week engagement patterns identify users at the greatest risk for early dropout, to inform development of potential "rescue" interventions?

methodsData from web users were drawn from EX, a freely available, multimodal digital intervention for tobacco cessation (N=70,265). First-week engagement was operationalized as any website page views or SMS text message responses within 1 week after registration. Early dropout was defined as having no subsequent engagement after that initial week through 1 year. First, a multivariate regression model was used to predict early dropout. Model predictors were dichotomous measures of engagement in each of the initial 6 days (days 2-7) following registration (day 1). Next, 6 univariate regression models were compared in terms of their discrimination ability to predict early dropout. The sole predictor of each model was a dichotomous measure of whether users had reengaged with the intervention by a particular day of the first week (calculated separately for each of 2-7 days).

resultsFor RQ1, the area under the receiver operating characteristic curve (AUC) of the multivariate model in predicting dropout after 1 week was 0.72 (95% CI 0.71-0.73), which was within the range of AUC metrics found in the study by Bricker and colleagues. For RQ2, the AUCs of the univariate models increased with each successive day until day 4 (0.66, 95% CI 0.65-0.67). The sensitivity of the models decreased (range 0.79-0.59) and the specificity increased (range 0.48-0.73) with each successive day.

conclusionsThis study provides independent validation of the use of first-week engagement to predict early dropout, demonstrating that the method generalizes across intervention modalities and engagement metrics. As digital intervention researchers continue to address the challenges of low engagement and early dropout, these results suggest that first-week engagement is a useful construct with predictive validity that is robust across interventions and definitions. Future research should explore the applicability and efficiency of this model to develop interventions to increase retention and improve health behavioral outcomes.

Indexed as

Patient DropoutsAdultFemaleHumansInternetMaleMiddle AgedSmoking CessationText MessagingTobacco Use Cessationattritioncessationdigital interventionsdropoutengagementinternetmobile healthmobile phonesmokingtobacco

Identifiers

PMID39602788
PMCPMC11635322

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.