Evidence map›Paper›PMID 39602421›Full record

ArticleMMWR. Morbidity and mortality weekly report2024

Progress Toward UNAIDS Global HIV Pre-Exposure Prophylaxis Targets: CDC-Supported Oral Pre-Exposure Prophylaxis - 37 Countries, 2017─2023.

Megan E Peck, Stephanie Davis, Elijah Odoyo-June, Jonathan Mwangi, Elvis Oyugi, Thai Hoang, Marcos Canda, Jessica Seleme, Maria Bock, Lylie Ndeikemona and 26 more

Abstract read
In one paragraph

Article in MMWR. Morbidity and mortality weekly report, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
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  12. Lenacapavir for HIV Prevention in Africa: Opportunities, Barriers, and Policy Priorities.Journal of the International Association of Providers of AIDS Care
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors.

Megan E Peck
Stephanie Davis
Elijah Odoyo-June
Jonathan Mwangi
Elvis Oyugi
Thai Hoang
Marcos Canda
Jessica Seleme
Maria Bock
Lylie Ndeikemona
Sibongile Dladla
Richard Machava
Nyagonde Nyagonde
Abdul Mashauri
Anna Colletar Awor
Stella Alamo
Omega Chituwo
Tina Chisenga
Rickie Malaba
Miriam Mutseta
Carrine Angumua
Kingsly Tse Nkwoh
Janique Ricketts
Kelly-Ann Gordon-Johnson
Victor Adamu
Scott Adamu-Oyegun
John Mondi Benson
Sudhir Bunga
Nasim Farach
Carlos Castaneda
Luis Bonilla
Sharmeen Premjee
Hanna B Demeke
Gaston Djomand
Carlos Toledo
Ramona Bhatia

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral pre-exposure prophylaxis (PrEP) reduces HIV acquisition risk from sex by 99% and from injection drug use by ≥74% when used as recommended. The Joint United Nations Programme on HIV/AIDS (UNAIDS) has set a goal of 21.2 million persons using (initiating or continuing) PrEP globally in 2025. In 2016, CDC, with the U.S. President's Emergency Plan for AIDS Relief, joined ministries of health to implement PrEP globally. PrEP is beneficial for persons at substantial risk for acquiring HIV, including but not limited to key populations, which include female sex workers, men who have sex with men, persons in prisons and other enclosed settings, persons who inject drugs, and transgender persons. Annual country targets were used to guide scale-up. In 2023, CDC supported 856,816 PrEP initiations, which represents nearly one quarter of the 3.5 million persons globally who either initiated or continued PrEP that year. During 2017-2023, CDC supported PrEP initiations for 2,278,743 persons, 96.0% of whom were in sub-Saharan Africa. More than one half (64.0%) were female and 44.9% were aged 15-24 years. Overall, CDC achieved 118.7% of its PrEP initiation targets for the 7-year period. Among PrEP initiations for key populations, the majority in sub-Saharan Africa were female sex workers, whereas in Southeast Asia, Eurasia, and the Americas, the majority were men who have sex with men. Continued rapid scale-up is needed to meet the UNAIDS goal to end HIV as a public health threat.

Indexed as

Centers for Disease Control and Prevention, U.S.Global HealthHIV InfectionsPre-Exposure ProphylaxisUnited NationsAdministration, OralAnti-HIV AgentsFemaleHumansMaleOrganizational ObjectivesProgram EvaluationUnited StatesAnti-HIV Agents

Identifiers

PMID39602421
PMCPMC11602022

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.