Evidence map›Paper›PMID 39602419›Full record

ArticlePloS one2024

Factors associated with self-reported suboptimal antiretroviral adherence and limited retention in care among people living with HIV who attend a large ART clinic in Panama City, Panama.

Amanda Gabster, Félix Díaz Fernández, Juan Miguel Pascale, Angelique Orillac, Samuel Moreno-Wynter, Casey D Xavier Hall, Eugenia Flores Millender, Frank Frankie Wong, Mónica Jhangimal, Anyi Yu-Pon and 5 more

Abstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Amanda GabsterInstituto Conmemorativo Gorgas de Estudios de la Salud, Panama.ORCID 0000-0002-7712-0444
Félix Díaz FernándezHospital Santo Tomás, Panama City, Panama.
Juan Miguel PascaleInstituto Conmemorativo Gorgas de Estudios de la Salud, Panama.
Angelique OrillacInstituto Conmemorativo Gorgas de Estudios de la Salud, Panama.
Samuel Moreno-WynterInstituto Conmemorativo Gorgas de Estudios de la Salud, Panama.
Casey D Xavier HallCenter of Population Sciences for Health Equity, College of Nursing, Florida State University, Tallahassee, FL, United States of America.
Eugenia Flores MillenderInstituto Conmemorativo Gorgas de Estudios de la Salud, Panama.
Frank Frankie WongInstituto Conmemorativo Gorgas de Estudios de la Salud, Panama.
Mónica JhangimalInstituto Conmemorativo Gorgas de Estudios de la Salud, Panama.
Anyi Yu-PonInstituto Conmemorativo Gorgas de Estudios de la Salud, Panama.
Cristel Rodríguez-VargasHospital Santo Tomás, Panama City, Panama.
Diógenes Arjona-MirandaInstituto Conmemorativo Gorgas de Estudios de la Salud, Panama.
Bárbara FuentesUniversidad Interamericana de Panama, Facultad de Medicina, Panama City, Panama.
Germán HenostrozaDivision of Infectious Diseases, University of Alabama Birmingham, Birmingham, AL, United States of America.
Ana Belén AraúzInstituto Conmemorativo Gorgas de Estudios de la Salud, Panama.

Funding

NHLBI NIH HHS L30 HL154217NHLBI NIH HHS L60 HL170367
6 · The paper itself

Abstract

backgroundThe prevalence of HIV in Panama is estimated to be 1.0%; only 71% of individuals on antiretroviral treatment (ART) were virally suppressed in 2022. This study aimed to describe the prevalence of suboptimal adherence (≥1 missed doses in previous four weeks) and limited retention in HIV care (≥1 missed HIV care appointments in previous 12 months) among adults (aged ≥18 years) who attended the most populous urban ART Clinic in Panama City.

methodsIn this cross-sectional study, participants completed a self-administered questionnaire. Univariable and bivariable analyses were used to describe the prevalence of suboptimal adherence and limited retention in HIV care. Multivariable logistic regression identified factors associated with suboptimal adherence at p<0.05.

resultsWe included 375 participants (209 identified as men, 158 as women, 8 another gender). Of those who responded, 37.3% (n = 125/335) reported suboptimal adherence: 28.6% (n = 53/185) of men, 49.0% (n = 71/145) women, 20.0% (n = 1/5) another gender; p<0.01; 18.6% (n = 69/371) reported limited retention in care:13.6% (n = 28/206) men, 24.2% (n = 38/157) women, 37.5% (n = 3/8) another gender, p = 0.01. In multivariable analyses, suboptimal adherence was associated with gender (49.0%women vs. 28.6% men, AOR = 1.86, 95%CI:0.97-3.57), depressive symptoms:46.2% severe symptoms vs. 28.1% minimal-mild, AOR = 2.19,95%CI:0.96-5.04), and lifetime intimate partner emotional violence (IPV) 48.2% vs.no emotional IPV 32.2%, OR = 1.96,95%CI:1.15-2.90, and lifetime physical IPV 46.9% vs.no physical IPV 32.6%, OR = 1.82, 95%CI:1.15-2.90. In unadjusted analyses, limited retention in care was associated with gender (24.2%women vs.13.6% men OR = 2.03, 95%CI:1.18-3.49), difficulty paying rent/mortgage/utilities (22.6% vs.14.9% no difficulty paying, OR = 1.67,95%CI = 0.98-2.83); no variables were associated in the multivariable model.

conclusionsThis study found high prevalence of suboptimal ART adherence and limited retention in care, especially among women; these factors were associated with severe depressive symptoms, as well as lifetime emotional and physical IPV. These results show the need for integrated mental health and IPV intervention for all individuals, including focused support for women.

Indexed as

Anti-HIV AgentsDrug MonitoringHIV InfectionsMedication AdherenceSelf ReportAdultCross-Sectional StudiesFemaleHumansMaleMiddle AgedPanamaRetention in CareSurveys and QuestionnairesYoung AdultAnti-HIV Agents

Identifiers

PMID39602419
PMCPMC11602065

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.