Evidence map›Paper›PMID 39602390›Full record

ArticleEnvironmental science & technology2024

Dose-Related Mutagenic and Clastogenic Effects of Benzo[

David M Schuster, Danielle P M LeBlanc, Gu Zhou, Matthew J Meier, Annette E Dodge, Paul A White, Alexandra S Long, Andrew Williams, Cheryl Hobbs, Alex Diesing and 4 more

Abstract read
In one paragraph

Article in Environmental science & technology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  6. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

David M SchusterDepartment of Biology, University of Ottawa, Ottawa K1N 6N5, Canada.ORCID 0009-0001-6316-4358
Danielle P M LeBlancEnvironmental Health Science and Research Bureau, Health Canada, Ottawa K1A 0K9, Canada.
Gu ZhouEnvironmental Health Science and Research Bureau, Health Canada, Ottawa K1A 0K9, Canada.
Matthew J MeierEnvironmental Health Science and Research Bureau, Health Canada, Ottawa K1A 0K9, Canada.ORCID 0000-0001-8199-8754
Annette E DodgeDepartment of Biology, University of Ottawa, Ottawa K1N 6N5, Canada.ORCID 0000-0002-0446-9055
Paul A WhiteDepartment of Biology, University of Ottawa, Ottawa K1N 6N5, Canada.
Alexandra S LongExisting Substances Risk Assessment Bureau, Health Canada, Ottawa K1A 0K9, Canada.ORCID 0000-0001-5862-6434
Andrew WilliamsEnvironmental Health Science and Research Bureau, Health Canada, Ottawa K1A 0K9, Canada.ORCID 0000-0002-7637-7686
Cheryl HobbsIntegrated Laboratory Systems, LLC, an Inotiv Company, Research Triangle Park 27560, North Carolina, United States.ORCID 0000-0003-1125-0868
Alex DiesingIntegrated Laboratory Systems, LLC, an Inotiv Company, Research Triangle Park 27560, North Carolina, United States.
Stephanie L Smith-RoeDivision of Translational Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park 27709, North Carolina, United States.
Jesse J SalkDepartment of Medicine, Division of Hematology and Oncology, University of Washington School of Medicine, Seattle 98195, Washington, United States.
Francesco MarchettiEnvironmental Health Science and Research Bureau, Health Canada, Ottawa K1A 0K9, Canada.
Carole L YaukDepartment of Biology, University of Ottawa, Ottawa K1N 6N5, Canada.ORCID 0000-0002-6725-3454

Funding

GENETIC TOXICOLOGY SUPPORT FOR THE NTP AND THE NIEHS75N96020C00001 · NIEHS · INTEGRATED LABORATORY SYSTEMS, LLC · PI HOBBS, CHERYL A. · 2020 to 2024
$4.1M
NIEHS NIH HHS 75N96020C00001
6 · The paper itself

Abstract

Polycyclic aromatic hydrocarbons (PAHs) are common environmental pollutants that originate from the incomplete combustion of organic materials. We investigated the clastogenicity and mutagenicity of benzo[

Indexed as

Micronucleus TestsMutagensAnimalsDNA DamageDose-Response Relationship, DrugFluorenesMaleMiceMutationFluorenesMutagensbenzo[b]fluoranthenebone marrowCOSMIC signaturesduplex sequencingenvironmental pollutantlivermutation spectrumpolycyclic aromatic hydrocarbons

Identifiers

PMID39602390
PMCPMC11636207

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.