Evidence map›Paper›PMID 39601917›Full record

ArticleMolecular genetics and genomics : MGG2024

WTAP increases BMP2 expression to promote osteoblast differentiation and inhibit osteoblast senescence via m

Bin Yue, Wei Zhang, Ming Li, Li Xu

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular genetics and genomics : MGG, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. WTAP Transcriptional Suppression by KLF9 Drives Osteoclastogenesis via MAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Review
  3. Article
  4. Targeting RNA adenosine editing and modification enzymes for RNA therapeutics.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bin YueDepartment of Endocrinology, Staff Hospital of Changqing Oilfield, Xi'an, 710018, China.
Wei ZhangDepartment of General Internal Medicine, Staff Hospital of Changqing Oilfield, No. 20, Changqing West Road, Jinghe Development Zone, Gaoling District, Xi'an, 710018, China. wei_zhg0@163.com.ORCID http://orcid.org/0009-0007-6540-5534
Ming LiDepartment of Orthopedics, Staff Hospital of Changqing Oilfield, Xi'an, 710018, China.
Li XuDepartment of Endocrinology, Staff Hospital of Changqing Oilfield, Xi'an, 710018, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pro-differentiation and anti-senescence treatment may be potential strategies for senile osteoporosis therapy. However, the regulatory mechanism underlying osteoblast differentiation and senescence in senile osteoporosis remain to be clarified. In the present study, the preosteoblast cell line MC3T3-E1 was used to induce osteoblast differentiation. The H

Indexed as

Bone Morphogenetic Protein 2Cell DifferentiationCellular SenescenceOsteoblastsSp1 Transcription FactorAdaptor Proteins, Signal TransducingAdenosineAnimalsCell LineCore Binding Factor Alpha 1 SubunitGene Expression RegulationHydrogen PeroxideMembrane ProteinsMethylationMiceOsteogenesisAdaptor Proteins, Signal TransducingAdenosineAtrnl1 protein, mouseBmp2 protein, mouseBone Morphogenetic Protein 2Core Binding Factor Alpha 1 SubunitHydrogen PeroxideMembrane ProteinsN-methyladenosineRNA Splicing FactorsSp1 Transcription FactorSp7 Transcription Factorm6AOsteoblast differentiationOsteoblast senescenceSp1WTAP

Identifiers

PMID39601917

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.