ArticleStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]2025
Is model-based dose calculation based on cone-beam computed tomography suitable for adaptive treatment planning in brachytherapy?
Article in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Experimental evaluation of an intraoperative-imaging based workflow for electron beam radiotherapy of pancreatic cancer using in situ dosimetry.Journal of applied clinical medical physics · 2026Article
- Geometric accuracy of surface high-dose rate brachytherapy applicator and catheters identified using Dixon volumetric interpolated breath-hold examination magnetic resonance images.Physics and imaging in radiation oncology · 2026Article
- Generation of 3D reference dosimetric datasets towards adoption of model-based dose calculations for permanent implant prostate brachytherapy.Medical physics · 2026Article
- Comparison of dose calculation approaches and clinical dose-response in image-guided head&neck brachytherapy of the oral cavity.Clinical and translational radiation oncology · 2025Article
- Establishing an intraoperative, mobile CBCT-based workflow for gynecologic brachytherapy: primary experience and benefit assessment.Frontiers in oncology · 2025Article
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Authors and funding
10 authors.
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Abstract
background and purposeModel-based dose calculation considering tissue compositions is increasingly being investigated in brachytherapy. The aim of this study was to assess the suitability of modern cone-beam computed tomography (CBCT) imaging compared to conventional computed tomography (CT) scans for this purpose. MATERIALS AND
methodsBy means of a phantom study, we evaluated the CT numbers and electron densities measured using a modern CBCT device as well as a conventional CT scanner for various materials. Based on this, we compared dose calculations (using the TG-43 formalism as well as model-based collapsed cone calculations assuming uniform materials [ACE
resultsThe comparison of ACE
conclusionModel-based dose calculation based on modern CBCT imaging was suitable. However, the found differences between these calculations and the TG-43 formalism should be investigated in dose-outcome analyses. The observed interfractional dosimetric variations revealed the importance of performing treatment quality assurance.
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