Evidence map›Paper›PMID 39601810›Full record

ArticleArchives of gynecology and obstetrics2025

Clinical comparison of laparoscopic and open surgical approaches for uterus-preserving myomectomy: a retrospective analysis on patient-reported outcome, postoperative morbidity and pregnancy outcomes.

Lucia Anna Otten, Subhiyeh Lama, Jakob Wilhelm Otten, Kira Winkler, Damian Johannes Ralser, Eva Katharina Egger, Mustea Alexander

Abstract readComparative Study
In one paragraph

Article in Archives of gynecology and obstetrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Accessory cavitated uterine mass: a rare cause of severe dysmenorrheaJournal of the Turkish German Gynecological Association · 2026
    Article
  3. A logistic regression model for predicting postoperative recurrence of cellular uterine leiomyoma.European journal of obstetrics & gynecology and reproductive biology: X · 2026
    Article
  4. Surgical management of uterine fibroids.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lucia Anna OttenClinic for Gynaecology and Gynaecological Oncology, Uniklinikum Bonn, Venusberg-Campus 1, 53127, Bonn, Germany. lucia.otten@ukbonn.de.
Subhiyeh LamaGastroenterology, Hepatology, General Internal Medicine, Helios Klinikum Siegburg, Ringstraße 49, 53721, Siegburg, Germany.
Jakob Wilhelm OttenClinic for Oral, Maxillofacial and Plastic Facial Surgery, Uniklinikum Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Kira WinklerDepartment of Senology, Uniklinikum Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Damian Johannes RalserClinic for Gynaecology and Gynaecological Oncology, Uniklinikum Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Eva Katharina EggerClinic for Gynaecology and Gynaecological Oncology, Uniklinikum Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Mustea AlexanderClinic for Gynaecology and Gynaecological Oncology, Uniklinikum Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeUterine fibroids pose clinical challenges due to varied symptoms and impact on fertility. Aim of this research is to compare open and laparoscopic myomectomy, with focus on evaluating their effects on patients' quality of life and analyzing their implications for pregnancy outcomes.

methodsThis retrospective study compares open and laparoscopic myomectomy outcomes in 168 patients treated October 2017 and July 2023. Preoperative characteristics and postoperative outcomes in terms of symptoms and pregnancy outcomes were examined.

resultsThe patient cohort comprised patients with a high symptom burden. Only 51.2% expressing a desire for future pregnancies, highlighting diverse motivations for uterus-preservation. No significant differences were observed in preoperative symptoms. Larger and multiple myomas were associated with a higher likelihood of laparotomy. Recurrence rates were lower after laparoscopy (10.2% vs. 23.8%, p = 0.02). Cesarean section recommendations were more frequent post-laparotomy group (36.6% vs. 86.6%, p = 0.000). Morbidities and satisfaction showed no significant differences between approaches, with slightly better bleeding improvement after laparotomy. Despite similar pregnancy outcomes, a high proportion of patients did not conceive postoperatively (75.4%). Among patients who became pregnant postoperatively (n = 31), most patients conceived after one year or more, with no dependence on the surgical approach (p = 0.227).

conclusionBoth open and laparoscopic myomectomy surgeries showed high patient satisfaction, symptom alleviation, and comparable pregnancy results. A preference emerged for laparoscopy in terms of cesarean section recommendations and recurrence risk. Laparoscopic procedures tended to offer higher operative satisfaction and fewer complications. The study emphasized the complexity of therapeutic decision-making.

Indexed as

LaparoscopyLeiomyomaOrgan Sparing TreatmentsPostoperative ComplicationsUterine MyomectomyUterine NeoplasmsAdultFemaleHumansLaparotomyPatient Reported Outcome MeasuresPregnancyPregnancy OutcomeQuality of LifeRetrospective StudiesGynecologyMinimal invasive surgeryMyomaUterine fibroids

Identifiers

PMID39601810
PMCPMC12033176

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.