ArticlemBio2025
CaMKII-dependent non-canonical RIG-I pathway promotes influenza virus propagation in the acute-phase of infection.
Abstract read
In one paragraph
Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Machine Learning and Experimental Verification Identify Anti-Influenza Natural Products.International journal of molecular sciences · 2026Article
- YWHAZ downregulated innate immune responses to RNA viruses by inhibiting the IRF3 signaling pathway.mSphere · 2026Article
- Reduced R-loop abundance at proinflammatory loci: a shared epigenetic mechanism in inflammatory and metabolic diseases.Frontiers in cardiovascular medicine · 2026Article
- Genetic Regulation of Immune Response in Dogs.Genes · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
26 authors.
Shinichiro HamaDepartment of Molecular Life Sciences, Graduate School of Life and Medical Sciences, Doshisha University, Kyotanabe, Japan.
Miho Watanabe-TakahashiDepartment of Molecular Life Sciences, Graduate School of Life and Medical Sciences, Doshisha University, Kyotanabe, Japan.ORCID 0000-0002-9659-8937
Hiroki NishimuraDepartment of Molecular Life Sciences, Graduate School of Life and Medical Sciences, Doshisha University, Kyotanabe, Japan.
Jumpei OmiDepartment of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Masakazu TamadaDepartment of Molecular Life Sciences, Graduate School of Life and Medical Sciences, Doshisha University, Kyotanabe, Japan.
Takashi SaitohDepartment of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, Hokkaido University of Science, Sapporo, Hokkaido, Japan.
Katsumi MaenakaLaboratory of Biomolecular Science and Center for Research and Education on Drug Discovery, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Hokkaido, Japan.
Yuta OkudaDepartment of Molecular Life Sciences, Graduate School of Life and Medical Sciences, Doshisha University, Kyotanabe, Japan.
Aoi IkegamiDepartment of Molecular Life Sciences, Graduate School of Life and Medical Sciences, Doshisha University, Kyotanabe, Japan.
Asami KitagawaDepartment of Molecular Life Sciences, Graduate School of Life and Medical Sciences, Doshisha University, Kyotanabe, Japan.
Koudai FurutaDepartment of Molecular Life Sciences, Graduate School of Life and Medical Sciences, Doshisha University, Kyotanabe, Japan.
Kana IzumiDepartment of Molecular Life Sciences, Graduate School of Life and Medical Sciences, Doshisha University, Kyotanabe, Japan.
Eiko ShimizuDepartment of Molecular Life Sciences, Graduate School of Life and Medical Sciences, Doshisha University, Kyotanabe, Japan.
Takashi NishizonoDepartment of Molecular Life Sciences, Graduate School of Life and Medical Sciences, Doshisha University, Kyotanabe, Japan.
Makoto FujiwaraDepartment of Molecular Life Sciences, Graduate School of Life and Medical Sciences, Doshisha University, Kyotanabe, Japan.
Tomohiro MiyasakaDepartment of Physiology and Anatomy, Faculty of Pharmacy, Nihon University, Funabashi, Japan.
Shigeo TakamoriLaboratory of Neural Membrane Biology, Graduate School of Brain Science, Doshisha University, Kyoto, Japan.
Hiroshi TakayanagiDepartment of Immunology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Keizo NishikawaDepartment of Cell Biology and Metabolic Biochemistry, Graduate School of Life and Medical Sciences, Doshisha University, Kyotanabe, Japan.
Toshihiko KobayashiDivision of Human Immunology, International Vaccine Design Center, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan.
Noriko Toyama-SorimachiDivision of Human Immunology, International Vaccine Design Center, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan.
Makoto YamashitaDepartment of Clinical Infectious Diseases, Aichi Medical University, Nagakute, Japan.
Toshiya SendaStructural Biology Research Center, Institute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), Tsukuba, Ibaraki, Japan.
Takatsugu HirokawaTransborder Medical Research Center, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Haruhiko BitoDepartment of Neurochemistry, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Kiyotaka NishikawaDepartment of Molecular Life Sciences, Graduate School of Life and Medical Sciences, Doshisha University, Kyotanabe, Japan.ORCID 0000-0002-2227-557X
Funding
Japan Agency for Medical Research and Development (AMED) JP21am0101093Japan Agency for Medical Research and Development (AMED) JP223fa627005Japan Agency for Medical Research and Development (AMED) JP22ama121029j0001MEXT | Japan Science and Technology Agency (JST) JPMJSP2129MEXT | Japan Society for the Promotion of Science (JSPS) 21H02629MEXT | Japan Society for the Promotion of Science (JSPS) 21K19344MEXT | Japan Society for the Promotion of Science (JSPS) 22H00432MEXT | Japan Society for the Promotion of Science (JSPS) JP20H05873Takeda Science Foundation (TSF)
Abstract
Ca
Indexed as
Calcium-Calmodulin-Dependent Protein Kinase Type 2DEAD Box Protein 58Influenza A virusOrthomyxoviridae InfectionsVirus ReplicationA549 CellsAnimalsDogsHost-Pathogen InteractionsHumansInfluenza, HumanInterferon Regulatory Factor-3Madin Darby Canine Kidney CellsMiceReceptors, ImmunologicSignal TransductionCalcium-Calmodulin-Dependent Protein Kinase Type 2Ddx58 protein, mouseDEAD Box Protein 58Interferon Regulatory Factor-3Receptors, ImmunologicRIGI protein, humanCaMKIIcap-snatchinginfluenza viruspeptide library screeningRIG-I
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.