Evidence map›Paper›PMID 39601460›Full record

ArticleMacromolecular bioscience2025

Salt-Responsive Switchable Block Copolymer Brushes with Antibacterial and Antifouling Properties.

Rafael Methling, Michael Greiter, Jiwar Al-Zawity, Mareike Müller, Holger Schönherr, Dirk Kuckling

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Macromolecular bioscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rafael MethlingDepartment of Chemistry, Paderborn University, Warburger Str. 100, 33098, Paderborn, Germany.
Michael GreiterPhysical Chemistry I, Research Center of Micro and Nanochemistry and (Bio)Technology (Cμ), University of Siegen, Adolf-Reichwein-Str. 2, 57076, Siegen, Germany.
Jiwar Al-ZawityPhysical Chemistry I, Research Center of Micro and Nanochemistry and (Bio)Technology (Cμ), University of Siegen, Adolf-Reichwein-Str. 2, 57076, Siegen, Germany.
Mareike MüllerPhysical Chemistry I, Research Center of Micro and Nanochemistry and (Bio)Technology (Cμ), University of Siegen, Adolf-Reichwein-Str. 2, 57076, Siegen, Germany.ORCID 0000-0003-0891-5160
Holger SchönherrPhysical Chemistry I, Research Center of Micro and Nanochemistry and (Bio)Technology (Cμ), University of Siegen, Adolf-Reichwein-Str. 2, 57076, Siegen, Germany.ORCID 0000-0002-5836-5569
Dirk KucklingDepartment of Chemistry, Paderborn University, Warburger Str. 100, 33098, Paderborn, Germany.ORCID 0000-0001-6003-151X

Funding

Hans-Böckler-Stiftung
6 · The paper itself

Abstract

A strategy for multifunctional biosurfaces exploiting multiblock copolymers and the antipolyelectrolyte effect is reported. Combining a polyzwitterionic/antifouling and a polycationic/antibacterial block with a central anchoring block for attachment to titanium oxide surfaces affords surface coatings that exhibit antifouling properties against proteins and allow for surface regeneration by clearing adhering proteins by employing a salt washing step. The surfaces also kill bacteria by contact killing, which is aided by a nonfouling block. The synthesis of block copolymers of 4-vinyl pyridine (VP), dimethyl 4-vinylbenzyl phosphonate (DMVBP), and 4-vinylbenzyltrimethyl ammonium chloride (TMA) is achieved on the multigram scale via RAFT polymerization with good end group retention and narrow dispersities. By polymer analogous reactions, poly(4-vinyl pyridinium propane sulfonate-block-4-vinylbenzyl phosphonic acid-block-4-vinylbenzyl trimethylammonium chloride) (P(VSP

Indexed as

Anti-Bacterial AgentsBiofoulingPolymersCoated Materials, BiocompatibleEscherichia coliQuaternary Ammonium CompoundsSaltsStaphylococcus aureusSurface PropertiesTitaniumAnti-Bacterial AgentsCoated Materials, BiocompatiblePolymersQuaternary Ammonium CompoundsSaltsTitaniumtitanium dioxideantibacterial coatingsantipolyelectrolyte effectsalt switchable polymerszwitterionic brushes

Identifiers

PMID39601460
PMCPMC11727821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.