Evidence map›Paper›PMID 39601354›Full record

Trial reportLiver international : official journal of the International Association for the Study of the Liver2025

Dietary Habits of Individuals With Primary Sclerosing Cholangitis-Poor Fat-Soluble Vitamin Intake and Dietary Quality.

Catarina Lindqvist, Michael Ingre, Stergios Kechagias, Emma Nilsson, Antonio Molinaro, Fredrik Rorsman, Annika Bergquist

Registry-linked trialAbstract readClinical Trial, Phase IIIMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Liver international : official journal of the International Association for the Study of the Liver, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04133792 (Effect of Simvastatin on the Prognosis of Primary Sclerosing Cholangitis), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04133792 phase3active not recruitingnot on this map

Effect of Simvastatin on the Prognosis of Primary Sclerosing Cholangitis (PSC); A Randomized, Double-blind, Placebo Controlled Multicenter Study

TypeinterventionalSponsorAnnika BergquistRan2020 to 2030Enrolled571ConditionsPrimary Sclerosing CholangitisArmsSimvastatin 40mg, Placebo oral tablet
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Catarina LindqvistSection Clinical Nutrition, Karolinska University Hospital, Stockholm, Sweden.ORCID 0000-0002-7082-9100
Michael IngreUnit of Gastroenterology and Hepatology, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.
Stergios KechagiasDepartment of Health, Medical, and Caring Sciences, Linköping University, Linköping, Sweden.ORCID 0000-0001-7614-739X
Emma NilssonDeparment of Surgery and Gastroenterology, Skåne University Hospital, Lund/Malmö, Sweden.
Antonio MolinaroWallenberg Laboratory, Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden.
Fredrik RorsmanDepartment of Gastroenterology and Hepatology, Uppsala University Hospital, Uppsala, Sweden.
Annika BergquistUnit of Gastroenterology and Hepatology, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-3858-6241

Funding

Stockholm County Council FoUI-974 513
6 · The paper itself

Abstract

BACKGROUND AND

aimsIndividuals with primary sclerosing cholangitis (PSC) have expressed a need for more dietary information. The aim of this study was to evaluate the dietary intake of individuals with PSC and compare it with Nordic nutrition recommendations 2023 (NNR2023).

methodsA cross-sectional assessment of dietary intake was performed using a food-frequency questionnaire among 120 individuals with PSC from five regions across Sweden. Macro- and micronutrient intake was compared to NNR2023. Dietary quality was evaluated using an index developed by the National Food Agency in Sweden.

resultsThe median age was 47 years (IQR 18), and median body mass index (BMI) was 25.2 kg/m

conclusionsMany individuals with PSC do not reach the recommended levels of various micronutrients, especially fat-soluble vitamins and report a poor dietary quality. The results highlight the need for a comprehensive approach to nutritional management in this population.

trial registrationClinicalTrials.gov identifier: NCT04133792.

Indexed as

Cholangitis, SclerosingDietFeeding BehaviorVitaminsAdultBody Mass IndexCross-Sectional StudiesFemaleHumansMaleMiddle AgedSwedenVitaminscholestatic liver diseasedietary intakemicronutrientsnutritionnutritional assessment

Identifiers

PMID39601354
PMCPMC11907217

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.