Evidence map›Paper›PMID 39601321›Full record

ArticleACS biomaterials science & engineering2024

Innervated Coculture Device to Model Peripheral Nerve-Mediated Fibroblast Activation.

Solsa Cariba, Avika Srivastava, Kendra Bronsema, Sonya Kouthouridis, Boyang Zhang, Samantha L Payne

Abstract read
In one paragraph

Article in ACS biomaterials science & engineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. The Role of the Nervous System in Lung Disease.Current neurology and neuroscience reports · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Solsa CaribaDepartment of Biomedical Sciences, University of Guelph, Guelph N1G 2W1, Canada.
Avika SrivastavaDepartment of Biomedical Sciences, University of Guelph, Guelph N1G 2W1, Canada.
Kendra BronsemaDepartment of Biomedical Sciences, University of Guelph, Guelph N1G 2W1, Canada.
Sonya KouthouridisDepartment of Chemical Engineering, McMaster University, Hamilton L8S 4L8, Canada.
Boyang ZhangDepartment of Chemical Engineering, McMaster University, Hamilton L8S 4L8, Canada.ORCID 0000-0002-2060-5555
Samantha L PayneDepartment of Biomedical Sciences, University of Guelph, Guelph N1G 2W1, Canada.ORCID 0000-0003-1256-0606

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cutaneous wound healing is a complex process involving various cellular and molecular interactions, resulting in the formation of a collagen-rich scar with imperfect function and morphology. Dermal fibroblasts are crucial to successful wound healing, migrating to the wound site where they are activated to provide extracellular matrix remodeling and wound closure. Peripheral nerves have been shown to play an important role in wound healing, with loss or damage to these nerves often leading to impaired healing and the formation of chronic nonhealing wounds. Previous research has suggested that sensory nerves secrete trophic factors that can regulate wound healing, including fibroblast activation; however, the direct cell-cell interaction between nerves and fibroblasts has not been extensively studied. To address this knowledge gap, we developed an

Indexed as

Coculture TechniquesFibroblastsWound HealingActinsAnimalsCell ProliferationCollagenGanglia, SpinalHumansPeripheral NervesActinsCollagenbioengineeringin vitro modelsregenerative medicinewound healing

Identifiers

PMID39601321
PMCPMC11633653

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.