Evidence map›Paper›PMID 39601280›Full record

ArticleEmerging microbes & infections2025

Origin, pathogenicity, and transmissibility of a human isolated influenza A(H10N3) virus from China.

Wenfei Zhu, Lei Yang, Xue Han, Min Tan, Shumei Zou, Xiyan Li, Weijuan Huang, Xiaoxu Zeng, Dayan Wang

Abstract read
In one paragraph

Article in Emerging microbes & infections, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wenfei ZhuNational Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention (China CDC), NHC Key Laboratory of Medical Virology and Viral Diseases, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Disease, Beijing, People's Republic of China.
Lei YangNational Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention (China CDC), NHC Key Laboratory of Medical Virology and Viral Diseases, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Disease, Beijing, People's Republic of China.
Xue HanNational Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention (China CDC), NHC Key Laboratory of Medical Virology and Viral Diseases, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Disease, Beijing, People's Republic of China.
Min TanNational Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention (China CDC), NHC Key Laboratory of Medical Virology and Viral Diseases, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Disease, Beijing, People's Republic of China.
Shumei ZouNational Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention (China CDC), NHC Key Laboratory of Medical Virology and Viral Diseases, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Disease, Beijing, People's Republic of China.
Xiyan LiNational Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention (China CDC), NHC Key Laboratory of Medical Virology and Viral Diseases, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Disease, Beijing, People's Republic of China.
Weijuan HuangNational Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention (China CDC), NHC Key Laboratory of Medical Virology and Viral Diseases, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Disease, Beijing, People's Republic of China.
Xiaoxu ZengNational Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention (China CDC), NHC Key Laboratory of Medical Virology and Viral Diseases, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Disease, Beijing, People's Republic of China.
Dayan WangNational Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention (China CDC), NHC Key Laboratory of Medical Virology and Viral Diseases, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Disease, Beijing, People's Republic of China.ORCID 0000-0002-4990-1016

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Subtype H10 viruses are known to infect humans in Africa, Oceania, and Asia. In 2021, 2022, and recently in April 2024, a novel H10N3 subtype avian influenza virus was found cause human infection with severe pneumonia. Herein, we comprehensively studied the phylogenetic evolution and biological characteristics of the newly emerged influenza A(H10N3) virus. We found that the human isolated H10N3 virus was generated in early 2019 in domestic poultry. The viruses bound to salic acid α2, 3 receptors, indicating their insufficient ability to infect humans. Although a low pathogenic avian influenza virus, the human isolated H10N3 virus exhibited robust pathogenicity in both BALB/c and C57BL/6 mice, with MLD

Indexed as

FerretsInfluenza A virusInfluenza, HumanInfluenza in BirdsMice, Inbred BALB CPhylogenyAnimalsChinaFemaleHumansMiceMice, Inbred C57BLOrthomyxoviridae InfectionsPoultryVirulenceInfluenza A(H10N3) virusesoriginpathogenicitytransmissibilityvirulence

Identifiers

PMID39601280
PMCPMC11632946

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.