Evidence map›Paper›PMID 39601216›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2025

Toward in vivo bronchoscopic functional CFTR assessment using a short circuit current measurement probe.

David O Otuya, Zhongyu Liu, Reny Joseph, Mohammed A Hanafy, Kadambari Vijaykumar, Denise Stanford, S Vamsee Raju, Elizabeth H Baker, Steven M Rowe, Guillermo J Tearney and 1 more

Abstract read
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

David O OtuyaWellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts, United States.ORCID 0000-0002-9334-9599
Zhongyu LiuGregory Fleming James Cystic Fibrosis Research Center, The University of Alabama at Birmingham, Birmingham, Alabama, United States.
Reny JosephGregory Fleming James Cystic Fibrosis Research Center, The University of Alabama at Birmingham, Birmingham, Alabama, United States.
Mohammed A HanafyGregory Fleming James Cystic Fibrosis Research Center, The University of Alabama at Birmingham, Birmingham, Alabama, United States.
Kadambari VijaykumarGregory Fleming James Cystic Fibrosis Research Center, The University of Alabama at Birmingham, Birmingham, Alabama, United States.
Denise StanfordGregory Fleming James Cystic Fibrosis Research Center, The University of Alabama at Birmingham, Birmingham, Alabama, United States.ORCID 0000-0003-4044-2113
S Vamsee RajuGregory Fleming James Cystic Fibrosis Research Center, The University of Alabama at Birmingham, Birmingham, Alabama, United States.
Elizabeth H BakerDepartment of Sociology, University of Alabama at Birmingham, Birmingham, Alabama, United States.
Steven M RoweGregory Fleming James Cystic Fibrosis Research Center, The University of Alabama at Birmingham, Birmingham, Alabama, United States.ORCID 0000-0001-9045-0133
Guillermo J TearneyWellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts, United States.
George M SolomonGregory Fleming James Cystic Fibrosis Research Center, The University of Alabama at Birmingham, Birmingham, Alabama, United States.ORCID 0000-0002-2969-5518

Funding

UAB CF Research and Translation Core CenterP30DK072482 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Brian R. Davis · 2007 to 2026
$23.0M
Bill and Melinda Gates Foundation (GF) OPP1135172Cystic Fibrosis Foundation (CFF) Solomon 20YOHHS | National Institutes of Health (NIH) P30NIDDK NIH HHS P30 DK072482
6 · The paper itself

Abstract

The epithelial lining of luminal organs provides an immune barrier against external factors and regulates the transport of nutrients, ions, and water into the body. Several conditions are associated with the breakdown or dysfunction of the epithelial lining. Short circuit current (

Indexed as

Cystic Fibrosis Transmembrane Conductance RegulatorAnimalsCystic FibrosisRatsCystic Fibrosis Transmembrane Conductance RegulatorAg/AgCl electrodeCFTRin situshort-circuit currentUssing chamber

Identifiers

PMID39601216
PMCPMC12633724

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.