ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2025
Tenascin C deletion impairs tendon healing and functional recovery after rotator cuff repair.
Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Nano-layered tendon patch to orchestrate timely interactions between tendon stem/progenitor cells and macrophages.Biomaterials · 2027Article
- Sequential vascular and neural changes underlying the progression of patellar tendinopathy.Journal of orthopaedic surgery and research · 2026Article
- Comparative effects of platelets and plasma-derived mitochondria in early-phase Achilles tendon inflammation.Regenerative biomaterials · 2026Article
- Research Progress on the Preparation and Application of Decellularized Tendons.Current issues in molecular biology · 2025Review
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Abstract
The biological factors that affect healing after rotator cuff repair (RCR) are not well understood. Genetic variants in the extracellular matrix protein Tenascin C (TNC) are associated with impaired tendon healing and it is expressed in rotator cuff tendon tissue after injury, suggesting it may have a role in the repair process. The purpose of the current study was to determine the role of TNC on tendon healing after RCR in a murine model. The supraspinatus tendon was transected and repaired on the left shoulder of wild-type (WT-RCR), Tenascin C null (Tnc
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