ArticleFrontiers in medicine2024
The relationship between high-sensitivity C-reactive protein and gallstones: a cross-sectional analysis.
Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Article
- Gallstone disease classification using SLOA-optimized CatBoost classifier with explainable AI.PloS one · 2026Article
- Gallstone Classification Using Random Forest Optimized by Sand Cat Swarm Optimization Algorithm with SHAP and DiCE-Based Interpretability.Sensors (Basel, Switzerland) · 2025Article
- Article
- The mediating role of inflammatory factors in the relationship between obesity and gallstone disease: evidence from the NHANES 2017-2020.European journal of medical research · 2025Article
- Positive association between cardiometabolic index and gallstones, with greater impact on women and those younger than 50 years: the NHANES 2017-2020 cross-sectional study.BMC public health · 2025Article
- Inflammatory burden index (IBI) and body roundness index (BRI) in gallstone risk prediction: insights from NHANES 2017-2020.Lipids in health and disease · 2025Article
- Association between weekend catch-up sleep and gallstone disease in US adults: a cross-sectional study from NHANES 2017-2020.Frontiers in public health · 2025Article
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5 authors.
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Abstract
Background and objective: High-sensitivity C-reactive protein (hs-CRP), a classical indicator of inflammation, holds significant clinical value in various diseases. The relationship between hs-CRP and gallstones, however, remains poorly studied at present. The relationship between hs-CRP and gallstones will be investigated in this study. Methods: Data from the 2017-2020 National Health and Nutrition Examination Survey (NHANES) were analyzed, focusing on participants aged 20 years and older who provided complete hs-CRP and gallstone information. Due to the skewed distribution of hs-CRP, the data were log-transformed [Log (hs-CRP)] to achieve normalization. Logistic regression analysis, subgroup analysis, and smoothed fitted curves were applied to determine the relationship between Log (hs-CRP) and the presence of gallstones. Results: The study included 4,484 participants with an average Log (hs-CRP) of 1.18 ± 0.74. The prevalence of gallstones was 11.15%, increasing with higher Log (hs-CRP) levels (quartile 1: 8.31%; quartile 2: 8.76%; quartile 3: 11.98%; quartile 4: 16.36%; Conclusion: Higher Log (hs-CRP) levels are linked to a greater prevalence of gallstones. We still need to carry out further large prospective research to explore the causal relationship of this association.
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