Evidence map›Paper›PMID 39600908›Full record

ReviewOncology reviews2024

Construction methods and latest applications of kidney cancer organoids.

Zhiqiang Li, Yanqiu You, Bingzheng Feng, Jibing Chen, Hongjun Gao, Fujun Li

Abstract readReview
In one paragraph

Review in Oncology reviews, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhiqiang LiMedical College of Guangxi University, Nan Ning, Guang Xi, China.
Yanqiu YouRuikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nan Ning, China.
Bingzheng FengRuikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nan Ning, China.
Jibing ChenRuikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nan Ning, China.
Hongjun GaoRuikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nan Ning, China.
Fujun LiMedical College of Guangxi University, Nan Ning, Guang Xi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal cell carcinoma (RCC) is one of the deadliest malignant tumors. Despite significant advances in RCC treatment over the past decade, complete remission is rarely achieved. Consequently, there is an urgent need to explore and develop new therapies to improve the survival rates and quality of life for patients. In recent years, the development of tumor organoid technology has attracted widespread attention as it can more accurately simulate the spatial structure and physiological characteristics of tumors within the human body. In this review, we summarize the main methods currently used to construct kidney cancer organoids, as well as their various biological and clinical applications. Furthermore, combining organoids with other technologies, such as co-culture techniques and microfluidic technologies, can further develop organoids and address their limitations, creating more practical models. This approach summarizes the interactions between different tissues or organs during tumor progression. Finally, we also provide an outlook on the construction and application of kidney cancer organoids. These rapidly evolving kidney cancer organoids may soon become a focal point in the development of

Indexed as

co-culturedrug screeningmicrofluidic deviceorganoidpersonalized treatmentrenal cell carcinomatumor microenvironment

Identifiers

PMID39600908
PMCPMC11588466

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.